Evidence map›Paper›PMID 37892428›Full record

ArticleNutrients2023

Vitamin D and Metabolic Syndrome in Working Age Subjects from an Obesity Clinic.

Luisella Vigna, Michela Carola Speciani, Amedea Silvia Tirelli, Francesca Bravi, Carlo La Vecchia, Caterina Conte, Francesca Gori

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Luisella VignaCentro Obesità e Lavoro, Unità di Salute Occupazionale, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0001-5014-721X
Michela Carola SpecianiLaboratorio di Statistica Medica, Dipartimento di Scienze Cliniche e di Comunità, Biometria ed Epidemiologia "G.A. Maccacaro", Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-7631-612X
Amedea Silvia TirelliCentro Obesità e Lavoro, Unità di Salute Occupazionale, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Francesca BraviLaboratorio di Statistica Medica, Dipartimento di Scienze Cliniche e di Comunità, Biometria ed Epidemiologia "G.A. Maccacaro", Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0003-0173-5319
Carlo La VecchiaLaboratorio di Statistica Medica, Dipartimento di Scienze Cliniche e di Comunità, Biometria ed Epidemiologia "G.A. Maccacaro", Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0003-1441-897X
Caterina ConteDipartimento di Promozione delle Scienze Umane e della Qualità della Vita, Università Telematica San Raffaele Roma, 00166 Rome, Italy.ORCID 0000-0001-7066-5292
Francesca GoriDipartimento di Anestesia, Rianimazione ed Emergenza Urgenza, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.ORCID 0000-0001-8330-5077
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITUniversity of Milan · ITMultiMedica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum vitamin D (VitD) levels have been inversely related with metabolic syndrome (MetS), although the direct impact of VitD is still debated. This study examined 879 subjects of working age from an obesity and occupational clinic in Milan, Italy. Among these participants, 316 had MetS, while 563 did not. A multiple logistic regression analysis was conducted to determine the odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) for MetS in relation to serum VitD levels. After controlling for age, sex, leisure time physical activity, and body mass index (BMI), individuals with VitD levels between 20 and 29.9 ng/dL, or at least 30 ng/dL, had approximately half the risk of developing MetS (OR: 0.52, 95% CI: 0.32-0.86 and OR: 0.50, 95% CI: 0.25-0.99, respectively) compared to those with VitD levels below 10 ng/dL. This study presents further evidence of the beneficial effect of adequate VitD levels on the risk of MetS in a population of overweight/obese workers, even after adjusting for BMI. This study supports the importance of testing for and-if required-supplementing VitD in individuals with metabolic risk factors.

Indexed as

Metabolic SyndromeVitamin D DeficiencyBody Mass IndexHumansObesityOverweightVitamin DVitaminsVitamin DVitaminsmetabolic syndromeobesityoverweightvitamin Dworkers

Identifiers

PMID37892428
PMCPMC10609594
OpenAlexW4387569221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.