Evidence map›Paper›PMID 37892403›Full record

ReviewNutrients2023

Linking Migraine to Gut Dysbiosis and Chronic Non-Communicable Diseases.

Manuela Di Lauro, Cristina Guerriero, Kevin Cornali, Maria Albanese, Micaela Costacurta, Nicola Biagio Mercuri, Nicola Di Daniele, Annalisa Noce

Abstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Selective loss and transcriptional reprogramming of Nox4The journal of headache and pain · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Health equity, care access and quality in headache - part 1.The journal of headache and pain · 2024
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Manuela Di LauroDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, RM, Italy.
Cristina GuerrieroDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, RM, Italy.ORCID 0000-0002-6104-6059
Kevin CornaliDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, RM, Italy.
Maria AlbaneseDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, RM, Italy.ORCID 0000-0002-5113-2017
Micaela CostacurtaDepartment of Surgical Sciences, University of Rome Tor Vergata, 00133 Rome, RM, Italy.
Nicola Biagio MercuriDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, RM, Italy.ORCID 0000-0001-6700-7491
Nicola Di DanieleDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, RM, Italy.ORCID 0000-0001-7671-0015
Annalisa NoceDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, RM, Italy.ORCID 0000-0003-1310-3730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the world, migraine is one of the most common causes of disability in adults. To date, there is no a single cause for this disorder, but rather a set of physio-pathogenic triggers in combination with a genetic predisposition. Among the factors related to migraine onset, a crucial role seems to be played by gut dysbiosis. In fact, it has been demonstrated how the intestine is able to modulate the central nervous system activities, through the gut-brain axis, and how gut dysbiosis can influence neurological pathologies, including migraine attacks. In this context, in addition to conventional pharmacological treatments for migraine, attention has been paid to an adjuvant therapeutic strategy based on different nutritional approaches and lifestyle changes able to positively modulate the gut microbiota composition. In fact, the restoration of the balance between the different gut bacterial species, the reconstruction of the gut barrier integrity, and the control of the release of gut-derived inflammatory neuropeptides, obtained through specific nutritional patterns and lifestyle changes, represent a possible beneficial additive therapy for many migraine subtypes. Herein, this review explores the bi-directional correlation between migraine and the main chronic non-communicable diseases, such as diabetes mellitus, arterial hypertension, obesity, cancer, and chronic kidney diseases, whose link is represented by gut dysbiosis.

Indexed as

Diabetes MellitusMigraine DisordersNoncommunicable DiseasesAdultDysbiosisHumansObesitychronic non-communicable diseasesgut microbiotalifestyle changesmigrainenutritional approaches

Identifiers

PMID37892403
PMCPMC10609600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.