Evidence map›Paper›PMID 37892325›Full record

ReviewChildren (Basel, Switzerland)2023

Seroprevalence of Dengue and Chikungunya Virus Infections in Children Living in Sub-Saharan Africa: Systematic Review and Meta-Analysis.

Neema Kayange, Duncan K Hau, Kevin Pain, Stephen E Mshana, Robert Peck, Stephan Gehring, Britta Groendahl, Philip Koliopoulos, Baraka Revocatus, Evarist B Msaki and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 6 countries.

Neema KayangeDepartment of Pediatrics, Bugando Medical Centre, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania.
Duncan K HauDepartment of Pediatrics, Weill Cornell Medical College, New York, NY 10065, USA.ORCID 0000-0001-5469-9011
Kevin PainSamuel J. Wood Library and C.V. Starr Biomedical Information Center, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.
Stephen E MshanaDepartment of Microbiology and Immunology, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania.ORCID 0000-0002-7526-6271
Robert PeckDepartment of Pediatrics, Bugando Medical Centre, Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza P.O. Box 1464, Tanzania.
Stephan GehringDepartment of Pediatrics, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Britta GroendahlDepartment of Pediatrics, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Philip KoliopoulosDepartment of Pediatrics, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Baraka RevocatusDepartment of Data and Statistics, Bugando Medical Centre, Mwanza P.O. Box 1370, Tanzania.
Evarist B MsakiDepartment of Epidemiology and Biostatistics, Bugando Medical Centre, Mwanza P.O. Box 1370, Tanzania.
Ombeva MalandeEast Africa Centre for Vaccines and Immunization (ECAVI), Kampala P.O. Box 3040, Uganda.
Cornell University · USJohannes Gutenberg University Mainz · DEBugando Medical Centre · TZCatholic University of Health and Allied Sciences · TZUniversity of Lusaka · ZM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue and chikungunya viruses are frequent causes of malarial-like febrile illness in children. The rapid increase in virus transmission by mosquitoes is a global health concern. This is the first systematic review and meta-analysis of the childhood prevalence of dengue and chikungunya in Sub-Saharan Africa (SSA). A comprehensive search of the MEDLINE (Ovid), Embase (Ovid), and Cochrane Library (Wiley) databases was conducted on 28 June 2019, and updated on 12 February 2022. The search strategy was designed to retrieve all articles pertaining to arboviruses in SSA children using both controlled vocabulary and keywords. The pooled (weighted) proportion of dengue and chikungunya was estimated using a random effect model. The overall pooled prevalence of dengue and chikungunya in SSA children was estimated to be 16% and 7%, respectively. Prevalence was slightly lower during the period 2010-2020 compared to 2000-2009. The study design varied depending on the healthcare facility reporting the disease outbreak. Importantly, laboratory methods used to detect arbovirus infections differed. The present review documents the prevalence of dengue and chikungunya in pediatric patients throughout SSA. The results provide unprecedented insight into the transmission of dengue and chikungunya viruses among these children and highlight the need for enhanced surveillance and controlled methodology.

Indexed as

chikungunya virusdengue virusprevalenceSub-Saharan Africasystematic review

Identifiers

PMID37892325
PMCPMC10605353
OpenAlexW4387421253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.