ReviewBiomolecules2023
The Hormesis Concept: Strengths and Shortcomings.
Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Dimethyl itaconate attenuates dextran sulfate sodium-induced ulcerative colitis in BALB/c mice: investigations on the TXNIP/NLRP3 inflammasome signaling pathway.Inflammopharmacology · 2026Article
- Kelulut Honey Modulates Skeletal Health and Bone-Related Molecular Markers in Rats Fed a High-Carbohydrate and High-Fat Diet.Life (Basel, Switzerland) · 2026Article
- Dietary mannitol improves salinity adaptation in Nile tilapia (Oreochromis niloticus) by enhancing ion regulation, energy metabolism and antioxidant defense.Fish physiology and biochemistry · 2026Article
- Design, Synthesis, and Biological Evaluation of Trifluoromethylated 1,2,4-Triazin-6-ones with Selective Antimycotic Activity and Hormesis Effects.International journal of molecular sciences · 2026Article
- Atmospheric Pressure Dielectric Barrier Discharge Plasma Treatment ofMolecules (Basel, Switzerland) · 2026Article
- Natural Mineral Water (Hora) Supplementation Improves Growth Performance and Carcass Characteristics of Sheep in Ethiopia.Veterinary medicine and science · 2026Article
- Exploring the neuroprotective, antioxidant, and anti-amyloid effects of Ganoderma lucidum compounds in Alzheimer's disease: insights from experimental and computational approaches.Journal, genetic engineering & biotechnology · 2026Article
- Sex-Specific Responses to Intermittent Fasting: A Narrative Review Across Physiological, Clinical, and Psychosocial Contexts.Nutrients · 2026Review
- Quaternary Phosphonium Salts Outperformed Vemurafenib (PLX) and Etoposide Against BRAFInternational journal of molecular sciences · 2026Article
- Reduced gravity and muon flux absence affectMicrobiology spectrum · 2026Article
- Oxalate induces proliferation and mitochondrial metabolism in select clear cell renal cell carcinoma cell lines.BMC cancer · 2026Article
- Flavonoids as a Potential Antifungal Alternative AgainstJournal of fungi (Basel, Switzerland) · 2026Article
- Unlocking the Secrets of Nature: Phytochemicals as Key Players in Longevity and Healthy Aging.Cell biochemistry and biophysics · 2026Review
- Chemical Profiling and Vascular Effects of a Hydroalcoholic Extract ofPlants (Basel, Switzerland) · 2026Article
- From Microbiota to Defense: The Preventive Effect and Mechanism of Total Flavonoids from Sea Buckthorn Leaves in DSS-Induced Colitis.Nutrients · 2026Article
- The differential effects of CBD and CBDA on viability and mRNA expression in colorectal cancer cells.Journal of cannabis research · 2026Article
- Per- and polyfluoroalkyl substances (PFAS) exposure and cardiovascular risk: lipid profile as a mediator.Lipids in health and disease · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hormesis implies that the effects of various materials or conditions that organisms are exposed to, may not have linear dose-response characteristics but rather, can be biphasic. Thus the response to a low dose of a stressor may be the opposite to that occurring at higher doses. Such a dual response is postulated for many toxicants and physical conditions and may involve a beneficial adaptive response. Such a non-linear effect is undoubtedly present in many useful pharmacological and nutraceutical agents with can be toxic at high concentrations. This somewhat divisive topic is an area of study that should be objectively studied and not clouded by political and policy considerations. The objective of this review is to examine claims concerning those exposures where hormesis seems to exist and also those where there is no good supporting evidence. The breadth of this phenomenon and potential mechanisms underlying hormetic events are discussed together with their limitations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.