Evidence map›Paper›PMID 37892152›Full record

ArticleBiomolecules2023

Circulating Small Extracellular Vesicles Reflect the Severity of Myocardial Damage in STEMI Patients.

Marta Zarà, Andrea Baggiano, Patrizia Amadio, Jeness Campodonico, Sebastiano Gili, Andrea Annoni, Gianluca De Dona, Maria Ludovica Carerj, Francesco Cilia, Alberto Formenti and 15 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  5. The role of nicotinamide adenine dinucleotide salvage enzymes in cardioprotection.Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 2 institutions in 1 country.

Marta ZaràCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Andrea BaggianoCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0002-8261-4529
Patrizia AmadioCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Jeness CampodonicoCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Sebastiano GiliCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Andrea AnnoniCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0001-5271-4353
Gianluca De DonaCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Maria Ludovica CarerjCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Francesco CiliaCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Alberto FormentiCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Laura FusiniCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0003-0309-6231
Cristina BanfiCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0003-3346-9879
Paola GripariCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Calogero Claudio TedescoCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Maria Elisabetta ManciniCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Mattia ChiesaCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0001-7427-9954
Riccardo MaragnaCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Francesca MarchettiCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Marco PensoCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0003-4040-6112
Luigi TassettiCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Alessandra VolpeCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0002-0624-0588
Alice BonomiCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Giancarlo MarenziCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Gianluca PontoneCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Silvia Stella BarbieriCentro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0002-7486-2637
Centro Cardiologico Monzino · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating small extracellular vesicles (sEVs) contribute to inflammation, coagulation and vascular injury, and have great potential as diagnostic markers of disease. The ability of sEVs to reflect myocardial damage assessed by Cardiac Magnetic Resonance (CMR) in ST-segment elevation myocardial infarction (STEMI) is unknown. To fill this gap, plasma sEVs were isolated from 42 STEMI patients treated by primary percutaneous coronary intervention (pPCI) and evaluated by CMR between days 3 and 6. Nanoparticle tracking analysis showed that sEVs were greater in patients with anterior STEMI (

Indexed as

Percutaneous Coronary InterventionST Elevation Myocardial InfarctionHumansInflammationMagnetic Resonance ImagingMyocardiumcardiac magnetic resonancemicrovascular obstructionmyocardial infarctionplateletssmall extracellular vesicles

Identifiers

PMID37892152
PMCPMC10605123
OpenAlexW4387230432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.