Evidence map›Paper›PMID 37892151›Full record

ArticleBiomolecules2023

Dendritic Cell Density and Morphology Can Be Used to Differentiate Vernal Keratoconjunctivitis from Allergic Conjunctivitis.

Zahra Tajbakhsh, Blanka Golebiowski, Fiona Stapleton, Ramin Salouti, M Hosein Nowroozzadeh, Mohammad Zamani, Nancy Briggs, Isabelle Jalbert

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. The Role of In Vivo Confocal Microscopy in Ocular Allergies.Turkish journal of ophthalmology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zahra TajbakhshSchool of Optometry and Vision Science, UNSW, Sydney, NSW 2052, Australia.ORCID 0000-0002-5432-1016
Blanka GolebiowskiSchool of Optometry and Vision Science, UNSW, Sydney, NSW 2052, Australia.
Fiona StapletonSchool of Optometry and Vision Science, UNSW, Sydney, NSW 2052, Australia.ORCID 0000-0002-7203-5443
Ramin SaloutiSalouti Cornea Research Center, Salouti Eye Clinic, Shiraz 71839-33636, Iran.
M Hosein NowroozzadehDepartment of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz 71348-14336, Iran.
Mohammad ZamaniSalouti Cornea Research Center, Salouti Eye Clinic, Shiraz 71839-33636, Iran.
Nancy BriggsStats Central, Mark Wainwright Analytical Centre, UNSW, Sydney, NSW 2052, Australia.
Isabelle JalbertSchool of Optometry and Vision Science, UNSW, Sydney, NSW 2052, Australia.ORCID 0000-0002-1351-0072
UNSW Sydney · AUShiraz University of Medical Sciences · IRThe University of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to compare the distribution of corneal and conjunctival epithelial dendritic cells (DCs) in vernal keratoconjunctivitis (VKC), allergic conjunctivitis (AC), and non-allergic controls to examine if the allergy type causes differences in immune cell activation. The prospective study included 60 participants: 20 with VKC, 20 with AC, and 20 non-allergic controls. In vivo confocal microscopy was performed on the right eye. The locations scanned included the corneal centre, inferior whorl, corneal periphery, corneal limbus, and bulbar conjunctiva. The DCs were counted manually, and their morphology was assessed for the largest cell body size, the presence of dendrites, and the presence of long and thick dendrites. The DC density was higher in VKC and AC compared to non-allergic group at all locations (

Indexed as

Conjunctivitis, AllergicConjunctivaCorneaDendritic CellsHumansProspective Studiesallergic conjunctivitisantigen capture capacitydendritic cellin vivo confocal microscopymigratory capacityvernal keratoconjunctivitis

Identifiers

PMID37892151
PMCPMC10605082
OpenAlexW4387186087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.