Evidence map›Paper›PMID 37892133›Full record

ArticleBiomolecules2023

A Desmethylphosphinothricin Dipeptide Derivative Effectively Inhibits

Maxim A Khomutov, Fabio Giovannercole, Laura Onillon, Marija V Demiankova, Byazilya F Vasilieva, Arthur I Salikhov, Sergey N Kochetkov, Olga V Efremenkova, Alex R Khomutov, Daniela De Biase

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Maxim A KhomutovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.ORCID 0000-0003-2833-9834
Fabio GiovannercoleDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Corso della Repubblica 79, I-04100 Latina, Italy.ORCID 0000-0003-0324-1398
Laura OnillonDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Corso della Repubblica 79, I-04100 Latina, Italy.
Marija V DemiankovaGause Institute of New Antibiotics, Bol'shaya Pirogovskaya 11, 119021 Moscow, Russia.
Byazilya F VasilievaGause Institute of New Antibiotics, Bol'shaya Pirogovskaya 11, 119021 Moscow, Russia.
Arthur I SalikhovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.
Sergey N KochetkovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.
Olga V EfremenkovaGause Institute of New Antibiotics, Bol'shaya Pirogovskaya 11, 119021 Moscow, Russia.ORCID 0000-0003-3131-1031
Alex R KhomutovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov Street 32, 119991 Moscow, Russia.ORCID 0000-0001-6833-7855
Daniela De BiaseDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Corso della Repubblica 79, I-04100 Latina, Italy.ORCID 0000-0003-3536-9927
Engelhardt Institute of Molecular Biology · RUGause Institute of New Antibiotics Russian Academy of Medical Sciences · RUSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New antibiotics are unquestionably needed to fight the emergence and spread of multidrug-resistant bacteria. To date, antibiotics targeting bacterial central metabolism have been poorly investigated. By determining the minimal inhibitory concentration (MIC) of desmethylphosphinothricin (Glu-γ-P

Indexed as

Bacillus subtilisDipeptidesAminobutyratesAnti-Bacterial AgentsEscherichia coliGlutamic AcidPhosphinic AcidsAminobutyratesAnti-Bacterial AgentsdesmethylphosphinothricinDipeptidesGlutamic AcidPhosphinic Acidsantibacterialantimicrobial resistancecentral metabolismdipeptide permeasesglutamate metabolismphosphorus-containing glutamate analogues

Identifiers

PMID37892133
PMCPMC10604730
OpenAlexW4387105405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.