ArticleDiagnostics (Basel, Switzerland)2023
The Clinical Value of Multimodal Ultrasound for the Differential Diagnosis of Hepatocellular Carcinoma from Other Liver Tumors in Relation to Histopathology.
Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 7 citations in OpenAlex.
- Enhanced diagnostic accuracy of contrast-enhanced ultrasound in liver space-occupying lesions: superior sensitivity and specificity over conventional ultrasound.American journal of cancer research · 2025Article
- Study Hotspot and Trend in the Field of Shear Wave Elastography: A Bibliometric Analysis from 2004 to 2024Current medical imaging · 2025Review
- Multi-Modality Ultrasound Model for Renal Fibrosis Assessment in Chronic Kidney Disease: Integrating Grayscale and Color Doppler Ultrasound Radiomics with Shear Wave Elastography.International journal of general medicine · 2025Article
- Prevalence and Risk Factors for Portal Cavernoma in Adult Patients with Portal Vein Thrombosis.Diagnostics (Basel, Switzerland) · 2024Article
- Utility of Alpha-Fetoprotein and Ultrasound in the Diagnosis and Prognosis of Patients with Hepatocellular Liver Cancer.Journal of multidisciplinary healthcare · 2024Article
- Diagnostic value of multimodal ultrasound for breast cancer and prediction of sentinel lymph node metastases.Frontiers in cell and developmental biology · 2024Article
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Authors and funding
5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Recent advances in the field of ultrasonography offer promising tools for the evaluation of liver tumors. We aim to assess the value of multimodal ultrasound in differentiating hepatocellular carcinomas (HCCs) from other liver lesions. We prospectively included 66 patients with 72 liver tumors. The histological analysis was the reference standard for the diagnosis of malignant liver lesions, and partially for benign tumors. All liver lesions were assessed by multiparametric ultrasound: standard ultrasound, contrast-enhanced ultrasound (CEUS), the point shear wave elastography (pSWE) using shear wave measurement (SWM) method and real-time tissue elastography (RTE). To diagnose HCCs, CEUS achieved a sensitivity, specificity, accuracy and positive predictive value (PPV) of 69.05%, 92.86%, 78.57% and 93.55%, respectively. The mean shear-wave velocity (Vs) value in HCCs was 1.59 ± 0.29 m/s, which was lower than non-HCC malignancies (
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