Evidence map›Paper›PMID 37891984›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Integrating Molecular Diagnostics and GIS Mapping: A Multidisciplinary Approach to Understanding Tuberculosis Disease Dynamics in South Africa Using Xpert MTB/RIF.

Lesley Erica Scott, Anne Nicole Shapiro, Manuel Pedro Da Silva, Jonathan Tsoka, Karen Rita Jacobson, Michael Emch, Harry Moultrie, Helen Elizabeth Jenkins, David Moore, Annelies Van Rie and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Geo-Enabling Public Health: A Systematic Review of GIS Applications.Advances in experimental medicine and biology · 2026
    Pooled it
  2. Article
  3. Closing gaps through innovation in the tuberculosis pathology value chain.Journal of clinical tuberculosis and other mycobacterial diseases · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 4 countries.

Lesley Erica ScottWits Diagnostic Innovation Hub, Faculty of Health Science, University of the Witwatersrand, Johannesburg 2093, South Africa.ORCID 0000-0001-6573-9525
Anne Nicole ShapiroDepartment of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.ORCID 0000-0002-5917-1440
Manuel Pedro Da SilvaWits Diagnostic Innovation Hub, Faculty of Health Science, University of the Witwatersrand, Johannesburg 2093, South Africa.ORCID 0000-0002-9869-5271
Jonathan TsokaWits Diagnostic Innovation Hub, Faculty of Health Science, University of the Witwatersrand, Johannesburg 2093, South Africa.ORCID 0009-0002-0337-7260
Karen Rita JacobsonDivision of Infectious Diseases, Boston Medical Center, Boston, MA 02118, USA.
Michael EmchDepartment of Epidemiology, University of North Carolina School, Chapel Hill, NC 27127, USA.ORCID 0000-0003-2642-965X
Harry MoultrieNational Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg 2192, South Africa.
Helen Elizabeth JenkinsDepartment of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.
David MooreDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Annelies Van RieFaculty of Medicine and Health Sciences, University of Antwerp, 2000 Antwerpen, Belgium.
Wendy Susan StevensWits Diagnostic Innovation Hub, Faculty of Health Science, University of the Witwatersrand, Johannesburg 2093, South Africa.
National Health Laboratory Service · ZABoston University · USUniversity of the Witwatersrand · ZABoston Medical Center · USUniversity of Antwerp · BEUniversity of London · GBUniversity of North Carolina at Chapel Hill · US

Funding

Evaluating the tuberculosis epidemic in South Africa using a novel ten-year cohortR01AI152126 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI JENKINS, HELEN E., SCOTT, LESLEY · 2020 to 2024
$1.6M
Combining Xpert and GIS to identify areas of high tuberculosis transmissionR21AI116015 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI SCOTT, LESLEY, VAN RIE, ANNELIES T.A. · 2015 to 2016
$356k
NIAID NIH HHS R01 AI152126NIAID NIH HHS R21 AI116015
6 · The paper itself

Abstract

An investigation was carried out to examine the use of national Xpert MTB/RIF data (2013-2017) and GIS technology for MTB/RIF surveillance in South Africa. The aim was to exhibit the potential of using molecular diagnostics for TB surveillance across the country. The variables analysed include

Indexed as

mycobacterial loadrifampicin resistanceSouth Africaspatial analysistuberculosisXpert MTB/RIF

Identifiers

PMID37891984
PMCPMC10606157
OpenAlexW4387498488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.