Evidence map›Paper›PMID 37891965›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Ellagic Acid Prevented Dextran-Sodium-Sulfate-Induced Colitis, Liver, and Brain Injury through Gut Microbiome Changes.

Dong-Ha Kim, Ji-Su Kim, Jae-Hee Kwon, In-Sook Kwun, Moon-Chang Baek, Gi-Seok Kwon, Wiramon Rungratanawanich, Byoung-Joon Song, Do-Kyun Kim, Hyo-Jung Kwon and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Dong-Ha KimDepartment of Molecular Medicine, School of Medicine, Cell & Matrix Research Institute, Kyungpook National University, Daegu 41566, Republic of Korea.
Ji-Su KimDepartment of Food and Nutrition, Andong National University, Andong 1375, Republic of Korea.
Jae-Hee KwonDepartment of Food and Nutrition, Andong National University, Andong 1375, Republic of Korea.ORCID 0000-0002-2793-2030
In-Sook KwunDepartment of Food and Nutrition, Andong National University, Andong 1375, Republic of Korea.
Moon-Chang BaekDepartment of Molecular Medicine, School of Medicine, Cell & Matrix Research Institute, Kyungpook National University, Daegu 41566, Republic of Korea.
Gi-Seok KwonDepartment of Horticulture & Medicinal Plant, Andong National University, Andong 1375, Republic of Korea.
Wiramon RungratanawanichSection of Molecular Pharmacology and Toxicology, Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.
Byoung-Joon SongSection of Molecular Pharmacology and Toxicology, Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-3954-3497
Do-Kyun KimKorea Zoonosis Research Institute, Jeonbuk National University, Iksan 54596, Republic of Korea.
Hyo-Jung KwonDepartment of Veterinary Pathology, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea.
Young-Eun ChoDepartment of Food and Nutrition, Andong National University, Andong 1375, Republic of Korea.ORCID 0000-0001-9864-0265
Gyeongguk National University · KRKyungpook National University · KRNational Institutes of Health · USChungnam National University · KR

Funding

Institute of Marketing and Social Information Technology No. 2021R1A4A1033078
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) affects millions of people worldwide and is considered a significant risk factor for colorectal cancer. Recent in vivo and in vitro studies reported that ellagic acid (EA) exhibits important antioxidant and anti-inflammatory properties. In this study, we investigated the preventive effects of EA against dextran sulfate sodium (DSS)-induced acute colitis, liver, and brain injury in mice through the gut-liver-brain axis. Acute colitis, liver, and brain injury were induced by treatment with 5% (

Indexed as

anti-inflammationantioxidantdextran sulfate sodiumellagic acidinflammatory bowel diseaseNF-κB/MAPK activation

Identifiers

PMID37891965
PMCPMC10604018
OpenAlexW4387822066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.