ArticleAntioxidants (Basel, Switzerland)2023
Differential Effects of Very-Low-Volume Exercise Modalities on Telomere Length, Inflammation, and Cardiometabolic Health in Obese Metabolic Syndrome Patients: A Subanalysis from Two Randomized Controlled Trials.
Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Combined training in hypoxic environments improves cardiometabolic health in older adults: a systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2025Pooled it
- Trial
- Trial
- Optimal exercise strategies to improve HDL-C in metabolic syndrome: A systematic review with pairwise, network, and dose-response meta-analysis.Journal of sport and health science · 2026Review
- The Impact of Weight Loss Secondary to Bariatric Surgery on Telomere Biology: A Narrative Review.Biomedicines · 2026Review
- Exercise-modulated IL-6 in cancer cachexia: molecular mechanisms and therapeutic potential.Journal of translational medicine · 2026Review
- A systematic review on the association of metabolic syndrome with telomere length and telomerase activity.Bioinformation · 2025Article
- Causal Relationship between Meat Intake and Biological Aging: Evidence from Mendelian Randomization Analysis.Nutrients · 2024Article
- Relationship between serum carotenoids and telomere length in overweight or obese individuals.Frontiers in nutrition · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Oxidative stress (OS) and inflammation are features of metabolic syndrome (MetS) that can contribute to the shortening of telomere length (TL), a marker of cellular ageing. Research indicates that exercise can positively influence MetS-associated conditions and TL. However, the effects of low-volume exercise types on TL are still unknown. We investigated the impact of very-low-volume high-intensity interval training (LV-HIIT), one-set resistance training (1-RT), and whole-body electromyostimulation (WB-EMS) on TL, inflammation, and cardiometabolic indices in 167 MetS patients. Data were derived from two randomized controlled trials where patients were allocated to an exercise group (2 sessions/week, for 12 weeks) or a control group. All groups received standard-care nutritional weight loss counselling. TL was determined as the T/S ratio (telomere to single-copy gene amount). All groups significantly reduced body weight (
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Registered trials
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