Evidence map›Paper›PMID 37891877›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Evaluation of Vitamin E Isoforms in Placental Tissue and Their Relationship with Maternal Dietary Intake and Plasma Concentrations in Mother-Infant Dyads.

Ishani Jhamb, Alyssa Freeman, Michelle R Lotfi, Matthew VanOrmer, Corrine Hanson, Ann Anderson-Berry, Melissa Thoene

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ishani JhambDepartment of Pediatrics, Division of Neonatology, University of California San Diego, San Diego, CA 92037, USA.ORCID 0000-0001-9791-4658
Alyssa FreemanDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Michelle R LotfiDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Matthew VanOrmerDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-1541-0155
Corrine HansonCollege of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Ann Anderson-BerryDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-8496-2543
Melissa ThoeneDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0001-8554-0708
University of Nebraska Medical Center · USUniversity of California San Diego · US

Funding

Child Health Research Institute N/aUniversity of Nebraska Medical Center Department of Pediatrics N/a
6 · The paper itself

Abstract

α-tocopherol is a vitamin E isoform with potent antioxidant activity, while the γ-tocopherol isoform of vitamin E exerts more pro-inflammatory effects. In maternal-fetal environments, increased plasma α-tocopherol concentrations are associated with positive birth outcomes, while higher γ-tocopherol concentrations are linked with negative pregnancy outcomes. However, little is known about tocopherol concentrations in placental tissue and their role in modulating placental oxidative stress, a process that is implicated in many complications of pregnancy. The objectives of this research are to evaluate the concentrations of α- and γ-tocopherol in placental tissue and assess relationships with maternal and umbilical cord plasma concentrations. A total of 82 mother-infant dyads were enrolled at the time of delivery, and maternal and umbilical cord blood samples and placenta samples were collected. α- and γ-tocopherol concentrations in these samples were analyzed by high-performance liquid chromatography (HPLC). γ-tocopherol concentrations demonstrated significant, positive correlations among all sample types (

Indexed as

placentapregnancytocopherolvitamin E

Identifiers

PMID37891877
PMCPMC10604073
OpenAlexW4386996052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.