ArticleBMC nephrology2023
Non-adherence, medication beliefs and symptom burden among patients receiving hemodialysis -a cross-sectional study.
Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03897231 (Prevalence of Non-adherence to Medication Among Patients on Chronic Hemodialysis - a Multicenter Cross-sectional Study), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence of Non-adherence to Medication Among Patients on Chronic Hemodialysis - a Multicenter Cross-sectional Study
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Correlates of symptom burden in renal dialysis patients: a systematic review and meta-analysis.Renal failure · 2024Pooled it
- Development and Psychometric Evaluation of the Peritoneal Dialysis Treatment Adherence Scale: A Multicenter Methodological Study.Healthcare (Basel, Switzerland) · 2026Article
- Association Between Pain Self-Efficacy and Adherence to Hemodialysis Regimen.Journal of clinical medicine · 2026Article
- The Effect of Medication Beliefs on Medication Adherence in Patients After TKA: A Moderated Mediation Model.International journal of behavioral medicine · 2026Article
- Article
- Shared decision making and decision aids in the management of kidney disease and renal replacement treatment options.Current opinion in nephrology and hypertension · 2026Review
- Prevalence and Predictors of Nonadherence to Treatment in Adult Patients Undergoing In-Centre Haemodialysis in Public Dialysis Units: A Quantitative Cross-Sectional Study.Nursing research and practice · 2026Article
- Symptom Burden and Patient-Reported Outcomes in Kidney Transplant Recipients: Results From the TransplantLines Biobank and Cohort Studies.Kidney medicine · 2026Article
- Development and Validation of the Treatment Adherence Scale for Non-Dialysis Chronic Kidney Disease Patients in China: A Mixed-Methods Study.Patient preference and adherence · 2026Article
- Patient health engagement as a moderator between perceived stress and treatment adherence among kidney failure patients undergoing hemodialysis: a cross-sectional analysis.Journal of behavioral medicine · 2025Article
- Medication Adherence and Perceptions According to the Presence or Absence of a Migration Background in a Dialysis Unit (DIANA Qualitative Study).Patient preference and adherence · 2025Article
- Analysis of the application effect of the Clark comfortable nursing approach in hemodialysis patients with end stage renal failure.Renal failure · 2024Article
- The Burden of Cardiovascular Disease and Geriatric Syndromes in Older Patients Undergoing Chronic Hemodialysis.International journal of environmental research and public health · 2024Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-adherence to medication is a common and complex issue faced by individuals undergoing hemodialysis (HD). However, more knowledge is needed about modifiable factors influence on non-adherence. This study investigated the prevalence of non-adherence, medication beliefs and symptom burden and severity among patients receiving HD in Denmark. Associations between non-adherence, medications beliefs and symptom burden and severity were also explored.
methodA cross-sectional questionnaire-based multisite study, including 385 participants. We involved patient research consultants in the study design process and the following instruments were included: Medication Adherence Report Scale, Beliefs about Medication Questionnaire and Dialysis Symptom Index. Logistic regression analysis was performed.
resultsThe prevalence of non-adherence was 32% (95% CI 27-37%) using a 23-point-cut-off. Just over one third reported being concerned about medication One third also believed physicians to overprescribe medication, which was associated with 18% increased odds of non-adherence. Symptom burden and severity were high, with the most common symptoms being tiredness/ lack of energy, itching, dry mouth, trouble sleeping and difficulties concentrating. A high symptom burden and/or symptom severity score was associated with an increased odd of non-adherence.
conclusionThe study found significant associations between non-adherence and, beliefs about overuse, symptom burden and symptom severity. Our results suggest health care professionals (HCP) should prioritize discussion about medication adherence with patients with focus on addressing patient-HCP relationship, and patients' symptom experience. Future research is recommended to explore the effects of systematically using validated adherence measures in clinical practice on medication adherence, patient-HCP communication and trust. Additionally, studies are warranted to further investigate the relationship between symptom experience and adherence in this population.
trial registrationNCT03897231.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.