ArticleBMC pediatrics2023
Comparison of respiratory pathogens in children with community-acquired pneumonia before and during the COVID-19 pandemic.
Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Efficacy and safety of nebulized drugs in the treatment of non-severeFrontiers in pharmacology · 2025Pooled it
- Application of targeted next-generation sequencing in children with community-acquired pneumonia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Epidemiological shifts and clinical characteristics of childhood Chlamydia pneumoniae pneumonia in Beijing before, during, and after public health interventions (2017-2025).BMC infectious diseases · 2026Article
- Rapid, sensitive, and highly specific detection ofMicrobiology spectrum · 2026Article
- Epidemiological characteristics of human parainfluenza virus infection in hospitalized children: a single-center study.Frontiers in public health · 2026Article
- Direct hospitalization costs of children withFrontiers in public health · 2026Article
- Comparison of Typical and Atypical Community Acquired Pneumonia Cases in Hospitalized Patients in Two Tertiary Centers in Riyadh, Saudi Arabia.Advances in respiratory medicine · 2025Article
- Epidemiology of Respiratory Adenovirus Infections Among Hospitalized Children in Hainan Province, China, 2021-2024.Pathogens (Basel, Switzerland) · 2025Article
- Resurgence of Mycoplasma pneumoniae infections in children: emerging challenges and opportunities.Current opinion in infectious diseases · 2025Review
- Altered microbiota of the lower respiratory tract and its association with COVID-19 severity analysed by metagenomics and metatranscriptomics.Communications biology · 2025Article
- Evidence-based guideline for the diagnosis and treatment ofPediatric investigation · 2025Article
- Prevalence and distribution of respiratory pathogens in pediatric acute respiratory infections in Putian, China.BMC infectious diseases · 2025Article
- Epidemiological characteristics of Mycoplasma pneumoniae and viral infections in hospitalized children with recurrent lower respiratory tract infections.American journal of translational research · 2025Article
- Emerging trends and concerns in Mycoplasma pneumoniae pneumonia among Chinese pediatric population.Pediatric research · 2024Article
- Analysis of respiratory pathogens in pediatric acute respiratory infections in Lanzhou, Northwest China, 2019-2024.Frontiers in cellular and infection microbiology · 2024Article
- Impact of normalized COVID-19 prevention and control measures on lower respiratory tract infection pathogenesis in hospitalized children.Frontiers in public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultifaceted non-pharmaceutical interventions during the COVID-19 pandemic have not only reduced the transmission of SARS-CoV2, but have had an effect on the prevalence of other pathogens. This retrospective study aimed to compare and analyze the changes of respiratory pathogens in hospitalized children with community-acquired pneumonia.
methodsFrom January 2019 to December 2020, children with community-acquired pneumonia were selected from the Department of Respiratory Medicine, Shanghai Children's Medical Center. On the first day of hospitalization, sputum, throat swabs, venous blood samples from them were collected for detection of pathogens.
resultsA total of 2596 children with community-acquired pneumonia were enrolled, including 1871 patients in 2019 and 725 in 2020. The detection rate in 2020 was lower than in 2019, whether single or multiple pathogens. Compared with 2019, the detection rate of virus, especially parainfluenza virus, influenza virus and respiratory syncytial virus, all decreased in 2020. On the contrary, the prevalence of human rhinovirus was much higher than that in 2019. In addition, the positivity rate for bacteria did not change much over the two years, which seemed to be less affected by COVID-19. And Mycoplasma pneumoniae which broke out in 2019 has been in low prevalence since March 2020 even following the reopening of school.
conclusionsStrict public health interventions for COVID-19 in China have effectively suppressed the spread of not only SARS-CoV2 but parainfluenza virus, influenza virus and Mycoplasma pneumonia as well. However, it had a much more limited effect on bacteria and rhinovirus. Therefore, more epidemiological surveillance of respiratory pathogens will help improve early preventive measures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.