Evidence map›Paper›PMID 37891452›Full record

ArticleInternal and emergency medicine2024

Diagnostic delay in symptomatic uncomplicated diverticular disease: an Italian tertiary referral centre study.

Giovanni Santacroce, Marco Vincenzo Lenti, Giulia Maria Abruzzese, Giacomo Alunno, Francesco Di Terlizzi, Carmine Frenna, Antonella Gentile, Mario Andrea Latorre, Clarissa Petrucci, Damiano Ruggeri and 6 more

Abstract read
In one paragraph

Article in Internal and emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Giovanni Santacroce *Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Marco Vincenzo Lenti *Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Giulia Maria AbruzzeseDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Giacomo AlunnoDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Francesco Di TerlizziDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Carmine FrennaDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Antonella GentileDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Mario Andrea LatorreDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Clarissa PetrucciDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Damiano RuggeriDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Simone SorianoDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Nicola AronicoFirst Department of Internal Medicine, San Matteo Hospital Foundation, Pavia, Italy.
Carlo Maria RossiDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Annalisa De SilvestriClinical Epidemiology and Biometric Unit, San Matteo Hospital Foundation, Pavia, Italy.
Gino Roberto CorazzaDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Antonio Di SabatinoDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy. a.disabatino@smatteo.pv.it.ORCID 0000-0002-0302-8645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The magnitude of the diagnostic delay of symptomatic uncomplicated diverticular disease (SUDD) is unknown; we aimed to evaluate SUDD diagnostic delay and its risk factors. SUDD patients diagnosed at a tertiary referral centre were retrospectively enrolled (2010-2022). Demographic and clinical data were retrieved. Overall, patient-, and physician-dependant diagnostic delays were assessed. Univariate and multivariate analyses were fitted to identify risk factors for diagnostic delay. Overall, 70 SUDD patients (median age 65 years, IQR 52-74; F:M ratio = 1.6:1) were assessed. The median overall diagnostic delay was 7 months (IQR 2-24), patient-dependant delay was 3 months (IQR 0-15), and physician-dependant delay was 1 month (IQR 0-6). Further, 25% of patients were misdiagnosed with irritable bowel syndrome (IBS). At multivariate analysis, previous misdiagnosis was a significant risk factor for overall and physician-dependant diagnostic delay (OR 9.99, p = 0.01, and OR 6.46, p = 0.02, respectively). Also, a high educational level (> 13 years) was associated with a greater overall diagnostic delay (OR 8.74 p = 0.02), while previous abdominal surgery was significantly associated to reduced physician-dependant diagnostic delay (OR 0.19 p = 0.04). To conclude, SUDD may be diagnosed late, IBS being the most frequent misdiagnosis. Timely diagnosis is crucial to tackle the burden of SUDD on patients and healthcare.

Indexed as

Diverticular DiseasesIrritable Bowel SyndromeAgedDelayed DiagnosisHumansItalyRetrospective StudiesTertiary Care CentersDiverticular diseaseIrritable bowel syndromeMisdiagnosisPatient education

Identifiers

PMID37891452
PMCPMC10827944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.