ArticleScientific reports2023
Natural course of perianal abscess in infants: a real-world study.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Treatment of perianal abscess and anal fistula in infants: a systematic review.Frontiers in surgery · 2025Pooled it
- Surgically Treated Perianal Abscess in Children: Clinical Characteristics and Subsequent Diagnosis of Crohn's Disease.European journal of pediatrics · 2026Article
- Conservative versus operative management of perianal abscess and fistula-in-ano in infants: a narrative review.Translational gastroenterology and hepatology · 2026Review
- Gut microbiota and relevant metabolites analysis in perianal abscess of infants.BMC microbiology · 2025Article
- Comparison of different treatment modalities for perianal abscess in infants: a retrospective cohort study.Scientific reports · 2025Article
- Risk factors for therapy failure after incision and drainage alone for perianal abscesses in children.Frontiers in pediatrics · 2024Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural course of perianal abscess (PA) in infancy remains obscure. This study aimed to investigate the natural course of infants with PA after conservative treatment. A retrospective cohort study was conducted in infants with PA who were treated conservatively (due to the parents' refusal of surgery), for more than 2 months between 2014 and 2020 at a single tertiary center. 153 patients (149 boys and 4 girls) were identified. The median follow-up was 5.3 years (range 3-8.2 years). Initially, 119 patients (77.8%) were completely cured by conservative treatment, and 34 (22.2%) failed. Among the 34 patients, 23 continued conservative treatment (20 cure, 3 fistula formation) and 11 underwent surgery. After conservative treatment, the rate of fistula formation, abscess recurrence, and new-onset abscess were 15.0%, 4.6%, and 6.5%, respectively. Overall, 139 patients (90.8%) were cured conservatively without surgery, and 11 (7.2%) underwent surgical management. In addition, 3 (2.0%) patients developed fistula-in-ano (under observation). PA in infants may be a time-limited and self-limited condition. Conservative management should be the first choice of treatment in most cases. Longer periods of conservative treatment may achieve better clinical outcomes in selected cases. There will be a percentage of patients (about 10%) that would require surgical treatment.
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