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ArticleActa obstetricia et gynecologica Scandinavica2024

Is the fetus fit for labor? Introducing fast-and-frugal trees (FFTrees) to simplify triage of women for STAN monitoring: An interobserver agreement comparison with traditional classification.

Susana Pereira, Petra Bakker, Ahmed Zaima, Tullio Ghi, Jörg Kessler, Susanna Timonen, Christoph Vayssière, Katrin Löser, Kaisa Holmberg, Yves Jacquemyn and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Methodological quality in reliability/agreement studies.Acta obstetricia et gynecologica Scandinavica · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Susana PereiraFetal Medicine Unit, The Royal London Hospital, Barts Health NHS Trust, London, UK.ORCID 0000-0002-7167-9052
Petra BakkerDepartment of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, The Netherlands.
Ahmed ZaimaDepartment of Obstetrics and Gynaecology, Kingston Hospital NHS Foundation Trust, London, UK.
Tullio GhiDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Jörg KesslerDepartment of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, and Department of Clinical Science, University of Bergen, Bergen, Norway.
Susanna TimonenDepartment of Obstetrics and Gynecology, Turku University Hospital, Turku, Finland.
Christoph VayssièreDepartment of Obstetrics and Gynecology, Paule de Viguier Hospital, Toulouse III University, Toulouse, France.
Katrin LöserDepartment of Obstetrics and Gynecology, South Jutland Hospital Aabenraa Campus, Aabenraa, Denmark.
Kaisa HolmbergDepartment of Obstetrics and Gynecology, Turku University Hospital, Turku, Finland.
Yves JacquemynDepartment of Obstetrics and Gynecology, Antwerp University Hospital, Edegem, and Global Health Institute, Antwerp University, Antwerp, Belgium.
Edwin ChandraharanGlobal Academy of Medical Education & Training, London, UK.ORCID 0000-0002-5711-8515
David WertheimSchool of Computing and Information Systems, Faculty of Science, Engineering and Computing, Kingston University, London, UK.ORCID 0000-0002-1672-3970
Per OlofssonInstitution of Clinical Sciences Malmö, Lund University, Malmö, Sweden.ORCID 0000-0002-0792-1393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIt is a shortcoming of traditional cardiotocography (CTG) classification table formats that CTG traces are frequently classified differently by different users, resulting in poor interobserver agreements. A fast-and-frugal tree (FFTree) flow chart may help provide better concordance because it is straightforward and has clearly structured binary questions with understandable "yes" or "no" responses. The initial triage to determine whether a fetus is suitable for labor when utilizing fetal ECG ST analysis (STAN) is very important, since a fetus with restricted capacity to respond to hypoxic stress may not generate STAN events and therefore may become falsely negative. This study aimed to compare physiology-focused FFTree CTG interpretation with FIGO classification for assessing the suitability for STAN monitoring. MATERIAL AND

methodsA retrospective study of 36 CTG traces with a high proportion of adverse outcomes (17/36) selected from a European multicenter study database. Eight experienced European obstetricians evaluated the initial 40 minutes of the CTG recordings and judged whether STAN was a suitable fetal surveillance method and whether intervention was indicated. The experts rated the CTGs using the FFTree and FIGO classifications at least 6 weeks apart. Interobserver agreements were calculated using proportions of agreement and Fleiss' kappa (κ).

resultsThe proportions of agreement for "not suitable for STAN" were for FIGO 47% (95% confidence interval [CI] 42%-52%) and for FFTree 60% (95% CI 56-64), ie a significant difference; the corresponding figures for "yes, suitable" were 74% (95% CI 71-77) and 70% (95% CI 67-74). For "intervention needed" the figures were 52% (95% CI 47-56) vs 58% (95% CI 54-62) and for "expectant management" 74% (95% CI 71-77) vs 72% (95% CI 69-75). Fleiss' κ agreement on "suitability for STAN" was 0.50 (95% CI 0.44-0.56) for the FIGO classification and 0.57 (95% CI 0.51-0.63) for the FFTree classification; the corresponding figures for "intervention or expectancy" were 0.53 (95% CI 0.47-0.59) and 0.57 (95% CI 0.51-0.63).

conclusionsThe proportion of agreement among expert obstetricians using the FFTree physiological approach was significantly higher compared with the traditional FIGO classification system in rejecting cases not suitable for STAN monitoring. That might be of importance to avoid false negative STAN recordings. Other agreement figures were similar. It remains to be shown whether the FFTree simplicity will benefit less experienced users and how it will work in real-world clinical scenarios.

Indexed as

ElectrocardiographyFetal MonitoringTriageCardiotocographyFemaleFetusHeart Rate, FetalHumansObserver VariationPregnancyRetrospective Studiescardiotocographyclassificationclinical guidelinesfast-and-frugal treefetal monitoringinterobserver agreementlabormidwiferyobstetricsSTAN

Identifiers

PMID37890863
PMCPMC10755137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.