Evidence map›Paper›PMID 37890484›Full record

ArticleStem cell reports2023

Businesses marketing purported stem cell treatments and exosome therapies for COVID-19: An analysis of direct-to-consumer online advertising claims.

Leigh Turner, Juan Ramon Martinez, Shemms Najjar, Thevin Rajapaksha Arachchilage, Jia Chieng Wang

Open access · goldAbstract read
In one paragraph

Article in Stem cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leigh TurnerProgram in Public Health, University of California, Irvine, 653 E. Peltason Drive, 2nd Floor, Irvine, CA 92697-3957, USA; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, USA; Department of Family Medicine, University of California, Irvine, Irvine, CA, USA. Electronic address: leigh.turner@uci.edu.
Juan Ramon MartinezProgram in Public Health, University of California, Irvine, 653 E. Peltason Drive, 2nd Floor, Irvine, CA 92697-3957, USA.
Shemms NajjarProgram in Public Health, University of California, Irvine, 653 E. Peltason Drive, 2nd Floor, Irvine, CA 92697-3957, USA.
Thevin Rajapaksha ArachchilageProgram in Public Health, University of California, Irvine, 653 E. Peltason Drive, 2nd Floor, Irvine, CA 92697-3957, USA.
Jia Chieng WangProgram in Public Health, University of California, Irvine, 653 E. Peltason Drive, 2nd Floor, Irvine, CA 92697-3957, USA.
University of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We identified 38 businesses advertising purported stem cell interventions and exosome products for COVID-19. These companies operated or facilitated access to 60 clinics. More than 75% of these clinics were based in the United States and Mexico. Thirty-six of the businesses marketed their stem cell and exosome products as treatments for Long COVID, six advertised them as "immune boosters," five claimed to treat patients in the acute infection phase, and two claimed their products were preventive. The least expensive product cost $2,950, the most expensive was $25,000, and the average listed cost for patients was $11,322. The promotion of these products is concerning because they have not been approved by national regulators and do not appear to be supported by convincing safety and efficacy data.

Indexed as

COVID-19ExosomesAdvertisingHumansMarketingPost-Acute COVID-19 SyndromeStem CellsUnited States

Identifiers

PMID37890484
PMCPMC10679647
OpenAlexW4387996541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.