Evidence map›Paper›PMID 37890274›Full record

ArticleThe Journal of surgical research2024

Identifying Factors Associated With Code Status Changes After Emergency General Surgery.

Shruthi Srinivas, Michael E Villarreal, Holly Baselice, Katherine C Bergus, Brittany Waterman, Katelyn Henderson, Sara Scarlet, Andrew J Young, Alex Helkin

Abstract read
In one paragraph

Article in The Journal of surgical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shruthi SrinivasDepartment of Trauma and Acute Care Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio. Electronic address: Shruthi.Srinivas@osumc.edu.
Michael E VillarrealDivision of Palliative Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Holly BaseliceDepartment of Trauma and Acute Care Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Katherine C BergusDepartment of Trauma and Acute Care Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Brittany WatermanDivision of Palliative Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Katelyn HendersonThe Ohio State University College of Medicine, Columbus, Ohio.
Sara ScarletDepartment of Trauma and Acute Care Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Andrew J YoungDepartment of Trauma and Acute Care Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Alex HelkinDepartment of Trauma and Acute Care Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Funding

The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9M
NCATS NIH HHS UL1 TR002733
6 · The paper itself

Abstract

introductionSurgical emergencies are time sensitive. Identifying patients who may benefit from preoperative goals of care discussions is critical to ensuring that operative intervention aligns with the patient's values. We sought to identify patient factors associated with acute changes in a patient's goals using code status change (CSC) as proxy.

methodsA retrospective analysis of single-institution data for patients undergoing urgent laparotomy was performed. Patients were stratified based on whether a postoperative CSC occurred. Parametric, nonparametric, and regression analyses were used to identify variables associated with CSC.

resultsOf 484 patients, 13.8% (n = 67) had a postoperative CSC. Patients with postoperative CSC were older (65 versus 60 years, P < 0.001). Odds of CSC were significantly higher in patients who were transferred between facilities (odds ratio [OR] 2.1), had a higher Charlson Comorbidity Index (3-4: OR 3.9, 5+: OR 6.8), and had a higher quick sequential organ failure assessment score (2: OR 5.0; 3: OR 38.7). Patients with anemia (OR 1.9) and active cancer (OR 3.0) had higher odds of CSC.

conclusionsTimely intervention in emergency general surgery may result in high-risk interventions and subsequent complications that do not align with a patient's goals and values. Our analysis identified a subset of patients who undergo surgery and have a postoperative CSC leading to transition to comfort-focused care. In these patients, a pause in clinical momentum may help ensure operative intervention remains goal concordant.

Indexed as

NeoplasmsPostoperative ComplicationsHumansLaparotomyRetrospective StudiesRisk FactorsComfort measures onlyDo not resuscitateEmergency general surgeryPostoperative complicationsSurgical futility

Identifiers

PMID37890274
PMCPMC10841616

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.