Evidence map›Paper›PMID 37889976›Full record

ArticleScience advances2023

Stromal BMP signaling regulates mucin production in the large intestine via interleukin-1/17.

Yalong Wang, Ruoyu Lou, Zhe Zhang, Chuyu Xiao, Shicheng Yu, Siting Wei, Yuan Liu, Wei Fu, Baojie Li, Ye-Guang Chen

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  8. Article
  9. Organoid Culture of Different Intestinal Segments from Human and Mouse.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Yalong WangThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0002-5477-4488
Ruoyu LouThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Zhe ZhangGuangzhou National Laboratory, Guangzhou 510005, China.
Chuyu XiaoThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Shicheng YuGuangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.ORCID 0000-0002-3737-8010
Siting WeiThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Yuan LiuThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0009-0002-2877-9354
Wei FuDepartment of General Surgery, Peking University Third Hospital, Beijing 100191, China.ORCID 0000-0001-5248-7891
Baojie LiBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0002-3913-1062
Ye-Guang ChenThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.ORCID 0000-0002-6701-0065
Center for Life Sciences · CNChinese Academy of Sciences · CNNanchang University · CNPeking University · CNShanghai Jiao Tong University · CNYunnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone morphogenic protein (BMP) signaling is critical for intestinal development, homeostasis, and function performance. Although the function of BMP signaling in the intestinal epithelium is well appreciated, the direct effect of BMP on intestinal stromal cells is poorly understood. Here, we show that disruption of BMP signaling by genetic ablation of

Indexed as

Colorectal NeoplasmsMucinsHumansInterleukin-1Interleukin-17Signal TransductionInterleukin-1Interleukin-17Mucins

Identifiers

PMID37889976
PMCPMC10610902
OpenAlexW4387969770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.