Evidence map›Paper›PMID 37889845›Full record

ArticleThe Journal of clinical endocrinology and metabolism2024

Trends and Components of Thyroid Status Evaluation in Commercially Insured Adults in the United States, 2006-2020.

Earl J Morris, Scott M Vouri, Spyridoula Maraka, Naykky Singh Ospina

Abstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Thyroid-Stimulating Hormone Levels and Depression in Older Adults: Cross-Sectional and Longitudinal Analyses in a Community-Dwelling Population.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026
    Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Earl J MorrisDepartment of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Scott M VouriDepartment of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.
Spyridoula MarakaDivision of Endocrinology and Metabolism, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Naykky Singh OspinaDivision of Endocrinology, Department of Medicine, University of Florida, Gainesville, FL 32608, USA.ORCID 0000-0001-7229-5061

Funding

Adequate selection of patients for thyroid biopsy: evaluation of a shared decision making conversation aidK08CA248972 · NCI · UNIVERSITY OF FLORIDA · PI SINGH OSPINA, NAYKKY · 2020 to 2024
$1.1M
Discontinuation of levothyroxine therapy for patients with subclinical hypothyroidism: a pilot randomized, double-blinded, placebo-controlled studyI21HX003268 · VA · CENTRAL ARKANSAS VETERANS HLTHCARE SYS · PI MARAKA, SPYRIDOULA · 2021 to 2022
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HSRD VA I21 HX003268NCI NIH HHS K08 CA248972NIH HHS K08CA248972
6 · The paper itself

Abstract

contextThyroid-stimulating hormone (TSH) is one of the most ordered laboratory tests.

objectiveDetermine trends of TSH testing rates and components of thyroid function testing.

methodsThis was a retrospective analysis of adults 18-64 years old without evidence of thyroid disease with at least 365 days of continuous enrollment between 2006 and 2020 in the IBM MarketScan Claims Database. The main outcome measures were trends of TSH tests/1000 eligible patient-months stratified by age, sex, and region and composition of thyroid function testing.

resultsAmong 67 353 280 patients meeting eligibility criteria, we identified 25 606 518 TSH tests and 15 138 211 patients with ≥1 TSH test. Patients contributing an episode of TSH testing were most commonly 45-54 years old (29.8%) and female (63.6%). TSH testing rates remained consistent throughout the study period with 11.4 and 11.7 TSH tests/1000 person-months in the first and last study months, respectively (mean 12.2 TSH tests/1000 person-months). TSH testing rates dropped sharply in the spring of 2020 (4.2 TSH tests/1000 person-months). Females showed a nearly 2-fold higher rate of TSH testing than males (16.1 TSH tests/1000 person-months vs 8.6 TSH tests/1000 person-months). TSH testing rates increased with age (8.2 TSH tests/1000 person-months among individuals 18-34 years old vs 15.4 TSH tests/1000 person-months among individuals 55-64 years old). No difference in TSH testing rates was noted between regions. Thyroid function testing episodes included only TSH in most cases (70.8%).

conclusionTSH testing rates among commercially insured individuals without known thyroid disease appears stable over time, with higher frequency in females and with increasing age.

Indexed as

Thyroid DiseasesAdolescentAdultChild, PreschoolFemaleHumansInfantMaleMiddle AgedRetrospective StudiesThyroid Function TestsThyrotropinThyroxineUnited StatesYoung AdultThyrotropinThyroxinethyroid dysfunctionthyroid testsTSH

Identifiers

PMID37889845
PMCPMC10876400

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.