Evidence map›Paper›PMID 37889723›Full record

ArticleAnimals : an open access journal from MDPI2023

An Outbreak of Limping Syndrome Associated with Feline Calicivirus.

Gianvito Lanave, Alessio Buonavoglia, Francesco Pellegrini, Barbara Di Martino, Federica Di Profio, Georgia Diakoudi, Cristiana Catella, Ahmed H Omar, Violetta I Vasinioti, Roberta Cardone and 3 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Gianvito LanaveDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.ORCID 0000-0003-4614-677X
Alessio BuonavogliaDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.ORCID 0000-0002-1044-2027
Francesco PellegriniDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.ORCID 0000-0003-0026-8472
Barbara Di MartinoDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0001-6192-7166
Federica Di ProfioDepartment of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.ORCID 0000-0002-7190-3835
Georgia DiakoudiDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.
Cristiana CatellaDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.ORCID 0000-0002-9594-5255
Ahmed H OmarDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.ORCID 0000-0001-6421-5041
Violetta I VasiniotiDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.
Roberta CardoneDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.ORCID 0000-0002-6104-677X
Giacinto SantoAndriavet Veterinary Clinic, 76123 Andria, Italy.
Vito MartellaDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.ORCID 0000-0002-5740-6947
Michele CameroDepartment of Veterinary Medicine, University Aldo Moro of Bari, 70010 Valenzano, Italy.
University of Bari Aldo Moro · ITUniversity of Teramo · IT

Funding

Ministero dell'Università e della ricerca Piano Nazionale di Ripresa e Resilienza PNRR Extended Partnership initiative on Emerging Infectious Diseases Project no. PE00000007, INF-ACTMinistry of Health Ricerca Corrente Grant number Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d'Aosta (IZS PLV) RC 02/20
6 · The paper itself

Abstract

Feline calicivirus (FCV) is a common viral pathogen found in domestic cats. FCV is highly contagious and demonstrates a high genetic variability. Upper respiratory tract disease, oral ulcerations, salivation, and gingivitis-stomatitis have been regarded as typical clinical signs of FCV infection. Ulcerative dermatitis, abortion, severe pneumonia, enteritis, chronic stomatitis, and virulent systemic disease have been reported more sporadically. Limping syndrome has been also described either in naturally or experimentally FCV-infected cats. In this study, we monitored a small outbreak of FCV infection in two household cats, in which limping disease was monitored with a 12-day lag time. The complete genome sequence was determined for the viruses isolated from the oropharyngeal and rectal swabs of the two animals, mapping up to 39 synonymous nucleotide mutations. The four isolates were sensitive to low pH conditions and trypsin treatment, a pattern usually associated with viruses isolated from the upper respiratory tract. Overall, the asynchronous pattern of infections and the results of genome sequencing suggest that a virus of respiratory origin was transmitted between the animals and that the FCV strain was able to retain the limping disease pathotype during the transmission chain, as previously observed in experimental studies with FCV strains associated with lameness.

Indexed as

catsfeline caliciviruslimping disease

Identifiers

PMID37889723
PMCPMC10251824
OpenAlexW4378574503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.