Evidence map›Paper›PMID 37889402›Full record

ArticleDrug delivery and translational research2024

Local delivery of doxorubicin prodrug via lipid nanocapsule-based hydrogel for the treatment of glioblastoma.

Mingchao Wang, Raphaël Bergès, Alessio Malfanti, Véronique Préat, Chiara Bastiancich

Open access · hybridAbstract read
In one paragraph

Article in Drug delivery and translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Mingchao WangUCLouvain, Louvain Drug Research Institute, Advanced Drug Delivery and Biomaterials, Avenue Mounier 73, 1200, Brussels, Belgium.
Raphaël BergèsAix-Marseille University, CNRS, INP, Inst Neurophysiopathol, 27 Boulevard Jean Moulin, Marseille, 13005, France.
Alessio MalfantiUCLouvain, Louvain Drug Research Institute, Advanced Drug Delivery and Biomaterials, Avenue Mounier 73, 1200, Brussels, Belgium.
Véronique PréatUCLouvain, Louvain Drug Research Institute, Advanced Drug Delivery and Biomaterials, Avenue Mounier 73, 1200, Brussels, Belgium. veronique.preat@uclouvain.be.
Chiara BastiancichUCLouvain, Louvain Drug Research Institute, Advanced Drug Delivery and Biomaterials, Avenue Mounier 73, 1200, Brussels, Belgium. chiara.bastiancich@univ-amu.fr.ORCID 0000-0003-2758-5654
Solvay (Belgium) · BECentre National de la Recherche Scientifique · FR

Funding

Canceropôle Provence-Alpes-Côte d'Azur Emergence 2021Fondation ARC ARCPJA12020060002222Fondation ARC PDF20190509176Fonds De La Recherche Scientifique - FNRS 33669945Fonds De La Recherche Scientifique - FNRS 40000747Fonds De La Recherche Scientifique - FNRS 40003419HORIZON EUROPE Marie Sklodowska-Curie Actions 887609Société Française de Pharmacie Oncologique and Académie Nationale de Pharmacie Elie Bzoura 2021
6 · The paper itself

Abstract

Glioblastoma (GBM) recurrences appear in most cases around the resection cavity borders and arise from residual GBM cells that cannot be removed by surgery. Here, we propose a novel treatment that combines the advantages of nanomedicine and local drug delivery to target these infiltrating GBM cells. We developed an injectable lipid nanocapsule (LNC)-based formulation loaded with lauroyl-doxorubicin prodrug (DOXC

Indexed as

Brain NeoplasmsDoxorubicinGlioblastomaHydrogelsLipidsNanocapsulesProdrugsAnimalsAntibiotics, AntineoplasticCell Line, TumorDrug Delivery SystemsDrug LiberationHumansMiceMice, Inbred C57BLAntibiotics, AntineoplasticDoxorubicinHydrogelsLipidsNanocapsulesProdrugsDoxorubicinGlioblastomaHydrogelLipid nanocapsulesLocal delivery

Identifiers

PMID37889402
PMCPMC11499358
OpenAlexW4387965537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.