Evidence map›Paper›PMID 37889386›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024

A concept elicitation study to understand the relationship between sleep and pain in rheumatoid arthritis and axial spondyloarthritis.

Kimberly Raymond, Wen-Hung Chen, Marguerite Bracher, April Foster, Andrew Lovley, Cory Saucier, Kristi Jackson, Eleanor J McDermott

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kimberly RaymondQualityMetric Incorporated, Johnston, RI, USA.ORCID http://orcid.org/0000-0001-9096-9269
Wen-Hung ChenGSK, Global Value Evidence and Outcomes, 1250 South Collegeville Road, Building 4, 4th floor, Collegeville, PA, 19426, USA. wen-hung.x.chen@gsk.com.ORCID http://orcid.org/0000-0002-6610-9709
Marguerite BracherGSK, Global Value Evidence and Outcomes, Stevenage, UK.ORCID http://orcid.org/0000-0001-9423-6097
April FosterQualityMetric Incorporated, Johnston, RI, USA.ORCID http://orcid.org/0000-0002-9663-7510
Andrew LovleyQualityMetric Incorporated, Johnston, RI, USA.ORCID http://orcid.org/0000-0001-9118-0673
Cory SaucierQualityMetric Incorporated, Johnston, RI, USA.ORCID http://orcid.org/0000-0002-0420-6458
Kristi JacksonQualityMetric Incorporated, Johnston, RI, USA.ORCID http://orcid.org/0000-0003-0081-5165
Eleanor J McDermottGSK, Real-World Study Delivery, Stevenage, UK.ORCID http://orcid.org/0000-0001-6302-4171
GroundMetrics (United States) · USAge UK · GBSouth College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis qualitative study (GSK study: 213635) was designed to better understand sleep disturbance as experienced by individuals with rheumatoid arthritis (RA) or axial spondyloarthritis (axSpA), and the relationship between sleep disturbance and pain and other aspects of the disease and disease activity.

methodsSixty-minute, one-on-one, concept elicitation interviews were conducted with 30 participants (15 with RA and 15 with axSpA) from the US. Interviews were audio-recorded and transcribed verbatim. Interview transcripts were coded and analyzed to explore themes related to pain and sleep disturbance, and relationships among those themes.

resultsPain was a prominent driver of sleep disturbance; 12 participants with RA (80%) and 14 with axSpA (93%) reported that pain impacted their ability to fall asleep, while all 15 with RA (100%) and 14 with axSpA (93%) reported that pain impacted their ability to stay asleep. Two-thirds of participants with RA (67%) or axSpA (60%) described a bi-directional relationship, whereby pain worsened sleep disturbance and sleep disturbance further aggravated pain. Factors other than pain, such as fatigue and emotional health, were also reported as important contributors to sleep disturbance (RA: n = 12/15, 80%; axSpA: n = 14/15, 93%). Participants with RA or axSpA described complex interconnections between fatigue, emotional health, pain, and sleep, often labeling these relationships as "vicious cycles". Notably, half of all participants reported sleep disturbance occurring without pain or other understood causes.

conclusionThese perspectives collected from people with RA or axSpA suggest that reducing sleep disruption directly may offer clinically relevant benefits.

Indexed as

Arthritis, RheumatoidAxial SpondyloarthritisSleep Wake DisordersSpondylitis, AnkylosingFatigueHumansPainQuality of LifeAxial spondyloarthritisPainPatient perspectiveQualitative studyRheumatoid arthritisSleep disturbance

Identifiers

PMID37889386
PMCPMC10850285
OpenAlexW4387965065

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.