Evidence map›Paper›PMID 37889290›Full record

ReviewEuropean journal of pediatrics2024

Mediastinitis secondary to invasive infection by group A Streptococcus in Spain.

I Mellado-Sola, E Cobo-Vázquez, A Calvo-Fernandez, E Cervantes, A Coca, B Calderón-Llopis, J Saavedra-Lozano, C Calvo, PedGAS-net group

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

I Mellado-Sola *Pediatric and Infectious Diseases Department, La Paz University Hospital, Institute for Health Research (IdiPAZ), Pº Castellana, 261, Madrid, 28046, Spain. imesola@gmail.com.
E Cobo-VázquezDepartment of Pediatrics. Hospital, Universitario Fundación de Alcorcón, Alcorcón, Madrid, Spain.
A Calvo-FernandezPediatric Intensive Care Unit, La Paz University Hospital, Madrid, Spain.
E CervantesPediatrics and Infectious Diseases Department, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain.
A CocaPediatric Intensive Care Unit, Ramón y Cajal University Hospital, Madrid, Spain.
B Calderón-LlopisPediatric Intensive Care Unit, La Paz University Hospital, Madrid, Spain.
J Saavedra-Lozano *Pediatric Infectious Diseases Unit, Department of Pediatrics, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
C Calvo *Pediatric and Infectious Diseases Department, La Paz University Hospital, Institute for Health Research (IdiPAZ), Pº Castellana, 261, Madrid, 28046, Spain.
PedGAS-net group
Universidad Complutense de Madrid · ESHospital Universitario La Paz · ESUniversidad Autónoma de Madrid · ESHospital La Paz Institute for Health Research · ESHospital Universitario Virgen de la Arrixaca · ESInstituto de Salud Carlos III · ESInstituto Cajal · ESSpanish Clinical Research Network · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes 5 mediastinitis cases secondary to invasive group A Streptococcus (iGAS) disease in a recent outbreak in Spain. Among 398 iGAS cases between January 2019-March 2023, 5 (1.3%) were mediastinitis, 4 occurring in December 2022, all secondary to pneumonia or deep neck infection. We outline the clinical outcome with a review of the scarce pediatric literature.  Conclusion: mediastinistis is a rare but severe complication of iGAS and a high level of suspicion is required to diagnose it. What is Known: • Group A Streptococcus can cause invasive and severe infections in children. • Mediastinitis is a severe complication from some bacterial infections, mainly secondary due to deep-neck abscesses. What is New: • Mediastinitis is an unrecognized complication due to an invasive group A Streptococcus (iGAS) infection. • In cases of a deep-neck abscess or complicated pneumonia a high clinical suspicion of iGAS mediastinitis is required, especially when the clinical course is not favorable.

Indexed as

MediastinitisPneumoniaStreptococcal InfectionsAbscessChildHumansSpainStreptococcus pyogenesDeep neck infectionsGroup A StreptococcusInvasive infectionsMediastinitisPneumonia

Identifiers

PMID37889290
OpenAlexW4387965576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.