Evidence map›Paper›PMID 37889262›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2023

The Stability and Validity of Automated Indices of Vocal Development in Infants With Autistic and Non-Autistic Siblings.

Jennifer E Markfeld, Jacob I Feldman, Claire Daly, Pooja Santapuram, Sarah M Bowman, Kacie Dunham-Carr, Evan Suzman, Bahar Keçeli-Kaysılı, Tiffany G Woynaroski

Open access · greenAbstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. The use of Language ENvironment Analysis in autism research: A systematic review.Autism : the international journal of research and practice · 2025
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jennifer E MarkfeldDepartment of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN.ORCID 0000-0002-7995-6077
Jacob I FeldmanDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0002-5723-5834
Claire DalyDepartment of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN.
Pooja SantapuramVanderbilt University School of Medicine, Nashville, TN.
Sarah M BowmanDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.
Kacie Dunham-CarrDepartment of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN.
Evan SuzmanMaster's Program in Biomedical Science, Vanderbilt University, Nashville, TN.ORCID 0000-0001-5265-336X
Bahar Keçeli-KaysılıDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.
Tiffany G WoynaroskiDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN.ORCID 0000-0001-6513-1181
Google (United States) · US

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Institutional Career Development CoreKL2TR002245 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$9.3M
NRSA Training CoreTL1TR002244 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$4.6M
Sensory Project in Infant/Toddler Siblings of Children with Autism (Project SPIS)R01DC020186 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Tiffany Woynaroski · 2022 to 2026
$3.2M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)KL2TR000446 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$2.8M
Sensory Project in Infant/Toddler Siblings of Children with Autism (Project SPIS)R21DC016144 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WOYNAROSKI, TIFFANY · 2017 to 2019
$474k
Looking to and Processing of Audiovisual Speech in Infants at Risk for AutismF31DC020129 · NIDCD · VANDERBILT UNIVERSITY · PI DUNHAM-CARR, KACIE · 2021 to 2024
$89k
NCATS NIH HHS KL2 TR000446NCATS NIH HHS KL2 TR002245NCATS NIH HHS TL1 TR002244NICHD NIH HHS P50 HD103537NIDCD NIH HHS F31 DC020129NIDCD NIH HHS R01 DC020186NIDCD NIH HHS R21 DC016144
6 · The paper itself

Abstract

purposeThis study evaluates the extent to which automated indices of vocal development are stable and valid for predicting language in infants at increased familial likelihood for autism and/or language impairment and relatively lower likelihood infants.

methodA group of infants with autistic siblings (Sibs-autism; 20 infants) and a comparison group of infants with non-autistic siblings (Sibs-NA; 20 infants) wore Language ENvironment Analysis (LENA) recording devices for 16 hr on 2 days within a 1-week period. Extant software was used to derive several putative indices of vocal development from these recordings. Stability of these variables was examined across and within groups. Expressive and receptive language aggregates were calculated for each participant. Multiple regression analyses were used to (a) evaluate zero-order correlations for variables derived from LENA recordings with concurrent and future language and (b) test whether those associations were moderated by group status.

resultsBoth stability and validity differed by variable and group status. All variables reached acceptable stability in the Sibs-autism group within two to three observations, whereas stability of most variables was attenuated in the Sibs-NA group. No variables were associated with concurrent language in the theoretically motivated direction across groups, but two variables were strongly associated with concurrent expressive language in only the Sibs-NA group. Additionally, two variables were associated with later expressive language, though these correlations were again stronger in the Sibs-NA versus Sibs-autism group.

conclusionsAlthough selected automated indices of vocal development were stable in Sibs-autism and/or valid for predicting expressive language within Sibs-NA, no scores showed strong, theoretically motivated associations with language within the Sibs-autism group. Automated indices of vocal development may, thus, have limited validity or clinical utility for predicting language development in infants at elevated familial likelihood for autism. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.24415735.

Indexed as

Autism Spectrum DisorderAutistic DisorderLanguage Development DisordersHumansInfantLanguageLanguage DevelopmentSiblings

Identifiers

PMID37889262
PMCPMC11001377
OpenAlexW4387965237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.