Evidence map›Paper›PMID 37889213›Full record

ArticleBrazilian journal of cardiovascular surgery2023

Prognostic Impact of Residual Moderate Mitral Regurgitation Following Valve-in-Valve Transcatheter Aortic Valve Implantation.

Tomasz Stankowski, Sleiman Sebastian Aboul-Hassan, Mohammed Salem, Kristin Rochor, Soeren Schenk, Temirlan Erkenov, Farzaneh Seifi Zinab, Anja Muehle, Volker Herwig, Axel Harnath and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Brazilian journal of cardiovascular surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Tomasz StankowskiDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.ORCID 0000-0003-2054-8199
Sleiman Sebastian Aboul-HassanDepartment of Cardiac Surgery, Medinet Heart Center Ltd., Nowa Sol, Poland.
Mohammed SalemDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Kristin RochorDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Soeren SchenkDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Temirlan ErkenovDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Farzaneh Seifi ZinabDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Anja MuehleDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Volker HerwigDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Axel HarnathDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Michel Pompeu SáDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, Pennsylvania, United States of America.
Basel RamlawiDepartment of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, Pennsylvania, United States of America.
Dirk FritzscheDepartment of Cardiac Surgery, Sana Heart Center Cottbus, Cottbus, Germany.
Bartłomiej PerekDepartment of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, Poznan, Poland.
Sana Klinikum · DEMain Line Health · USFoundation of Cardiac Surgery Development · PLPoznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe impact of mitral regurgitation (MR) on valve-in-valve transcatheter aortic valve implantation (VIV-TAVI) in patients with failed bioprostheses remains unclear. The purpose of this study was to assess the prognostic impact of residual moderate MR following VIV-TAVI.

methodsWe retrospectively analyzed 127 patients who underwent VIV-TAVI between March 2010 and November 2021. At least moderate MR was observed in 51.2% of patients before the procedure, and MR improved in 42.1% of all patients. Patients with postoperative severe MR, previous mitral valve intervention, and patients who died before postoperative echocardiography were excluded from further analyses. The remaining 114 subjects were divided into two groups according to the degree of postprocedural MR: none-mild MR (73.7%) or moderate MR (26.3%). Propensity score matching yielded 23 pairs for final comparison.

resultsNo significant differences were found between groups before and after matching in early results. In the matched cohort, survival probabilities at one, three, and five years were 95.7% vs. 87.0%, 85.0% vs. 64.5%, and 85.0% vs. 29.0% in the none-mild MR group vs. moderate MR-group, respectively (log-rank P=0.035). Among survivors, patients with moderate MR had worse functional status according to New York Heart Association (NYHA) class at follow-up (P=0.006).

conclusionMR is common in patients with failed aortic bioprostheses, and improvement in MR-status was observed in over 40% of patients following VIV-TAVI. Residual moderate MR after VIV-TAVI is not associated with worse early outcomes, however, it was associated with increased mortality at five years of follow-up and worse NYHA class among survivors.

Indexed as

Aortic Valve StenosisHeart Valve ProsthesisHeart Valve Prosthesis ImplantationMitral Valve InsufficiencyTranscatheter Aortic Valve ReplacementAortic ValveHumansPrognosisRetrospective StudiesTreatment OutcomeBioprosthesisFollow-Up StudiesMitral ValveMitral Valve InsufficiencyPrognosisPropensity ScoreRetrospective StudiesSurvivors

Identifiers

PMID37889213
PMCPMC10610905
OpenAlexW4387966430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.