ReviewJournal of the American Heart Association2023
Acute Heart Failure Is a Malignant Process: But We Can Induce Remission.
Review in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inferior Vena Cava Ultrasound for Decongestion Assessment in Acute Heart Failure: Systematic Review.Echocardiography (Mount Kisco, N.Y.) · 2026Pooled it
- Simultaneous vaccination against influenza and respiratory syncytial virus in high-risk heart failure patients.ESC heart failure · 2025Trial
- Cardiac Structure and Function and Pulmonary Congestion Across New York Heart Association Classes in Patients With Acute Heart Failure.Echocardiography (Mount Kisco, N.Y.) · 2026Observational
- Beyond Survival: Reframing Palliative Care in Survivors of Cardiogenic Shock Complicating Acute Myocardial Infarction.JACC. Advances · 2026Article
- Serum malondialdehyde predicts mortality in patients with acute heart failure.Redox biology · 2026Article
- FIB-4 index predicts short-term mortality in Vietnamese acute heart failure patients.American heart journal plus : cardiology research and practice · 2026Article
- Low Serum Lysophospholipids Predict Increased In-Hospital Mortality in Patients With Acute Heart Failure.Journal of the American Heart Association · 2026Observational
- M2 macrophage exosomes reverse heart failure post-myocardial infarction by suppressing type 1 interferon signaling in myeloid cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Diuretic resistance during emergency treatment of acute heart failure: incidence and correlation with 30-day readmission.American journal of translational research · 2026Article
- Sustained low-efficiency dialysis-an old method but possibly a new solution for environmental nephrology.Renal failure · 2025Review
- Nurse-coordinated multidisciplinary comprehensive heart failure management programme: A propensity-matched trial.ESC heart failure · 2025Article
- Nighttime Systolic Blood Pressure Determined by Pulse Transit Time Predicts Cardiac Events in Patients With Heart Failure.Journal of the American Heart Association · 2025Article
- Heart Failure-Focus on Kidney Replacement Therapy: Why, When, and How?International journal of molecular sciences · 2025Review
- Addressing 'Residual Congestion' to Improve Prognosis After Acute Heart Failure Decompensation.Cardiac failure review · 2025Review
- Congestion and systemic inflammation in acute heart failure: correlations and prognostic role.Frontiers in cardiovascular medicine · 2025Article
- The kinetics of CA125 levels as a prognostic marker for in-hospital mortality in patients with acute heart failure: a pilot study.Frontiers in cardiovascular medicine · 2025Article
- Targeting Sodium in Heart Failure.Journal of personalized medicine · 2024Review
- High-intensity care for GDMT titration.Heart failure reviews · 2024Review
- Causes of Hospitalization in Patients With Cardiorenal Syndrome Across the Spectrum of Ejection Fraction.International journal of heart failure · 2024Article
- Empowering European hospital pharmacists in the face of heart failure.European journal of hospital pharmacy : science and practice · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute heart failure is a common and increasingly prevalent condition, affecting >10 million people annually. For those patients who survive to discharge, early readmissions and death rates are >30% everywhere on the planet, making it a malignant condition. Beyond these adverse outcomes, it represents one of the largest drivers of health care costs globally. Studies in the past 2 years have demonstrated that we can induce remissions in this malignant process if therapy is instituted rapidly, at the first acute heart failure episode, using full doses of all available effective medications. Multiple studies have demonstrated that this goal can be achieved safely and effectively. Now the urgent call is for all stakeholders, patients, physicians, payers, politicians, and the public at large to come together to address the gaps in implementation and enable health care providers to induce durable remissions in patients with acute heart failure.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.