Evidence map›Paper›PMID 37889083›Full record

ArticleNucleic acids research2023

A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder.

Yunxia Wang, Ziqi Pan, Minjie Mou, Weiqi Xia, Hongning Zhang, Hanyu Zhang, Jin Liu, Lingyan Zheng, Yongchao Luo, Hanqi Zheng and 9 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. Interpretation of RNA Universe and Coding Potential Using IntRNA.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yunxia WangCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Ziqi PanCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Minjie MouCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-7619-2975
Weiqi XiaCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Hongning ZhangCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-7818-7915
Hanyu ZhangCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0002-4728-7702
Jin LiuCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Lingyan ZhengCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Yongchao LuoCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Hanqi ZhengCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Xinyuan YuCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Xichen LianCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Zhenyu ZengInnovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-ZJU Joint Research Center of Future Digital Healthcare, Hangzhou 330110, China.
Zhaorong LiInnovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-ZJU Joint Research Center of Future Digital Healthcare, Hangzhou 330110, China.
Bing ZhangInnovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-ZJU Joint Research Center of Future Digital Healthcare, Hangzhou 330110, China.
Mingyue ZhengCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Honglin LiCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Tingjun HouCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Feng ZhuCollege of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-8069-0053

Funding

Alibaba CloudAlibaba-Zhejiang University'Double Top-Class' Universities Projects 181201*194232101Fundamental Research Funds for Central University 2018QNA7023Information Technology Center of Zhejiang UniversityKey R&D Program of Zhejiang Province 2020C03010National High-Level Talents Special Supports Plan of ChinaNational Key R&D Program of China 2022YFC3400501National Natural Science Foundation of China 82373790Natural Science Foundation of Zhejiang Province LR21H300001Westlake Laboratory
6 · The paper itself

Abstract

RNAs play essential roles in diverse physiological and pathological processes by interacting with other molecules (RNA/protein/compound), and various computational methods are available for identifying these interactions. However, the encoding features provided by existing methods are limited and the existing tools does not offer an effective way to integrate the interacting partners. In this study, a task-specific encoding algorithm for RNAs and RNA-associated interactions was therefore developed. This new algorithm was unique in (a) realizing comprehensive RNA feature encoding by introducing a great many of novel features and (b) enabling task-specific integration of interacting partners using convolutional autoencoder-directed feature embedding. Compared with existing methods/tools, this novel algorithm demonstrated superior performances in diverse benchmark testing studies. This algorithm together with its source code could be readily accessed by all user at: https://idrblab.org/corain/ and https://github.com/idrblab/corain/.

Indexed as

Computational BiologyRNAAlgorithmsSoftwareRNA

Identifiers

PMID37889083
PMCPMC10682500

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.