Evidence map›Paper›PMID 37889009›Full record

ArticleGigaScience2022

Cellsnake: a user-friendly tool for single-cell RNA sequencing analysis.

Sinan U Umu, Karoline Rapp Vander-Elst, Victoria T Karlsen, Manto Chouliara, Espen Sønderaal Bækkevold, Frode Lars Jahnsen, Diana Domanska

Open access · goldAbstract read
In one paragraph

Article in GigaScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sinan U UmuDepartment of Pathology, Institute of Clinical Medicine, University of Oslo, Oslo 0372, Norway.ORCID 0000-0001-8081-7819
Karoline Rapp Vander-ElstDepartment of Pathology, Oslo University Hospital-Rikshospitalet, Oslo 0372, Norway.ORCID 0009-0006-8772-204X
Victoria T KarlsenDepartment of Pathology, Oslo University Hospital-Rikshospitalet, Oslo 0372, Norway.ORCID 0000-0003-0991-5058
Manto ChouliaraDepartment of Pathology, Oslo University Hospital-Rikshospitalet, Oslo 0372, Norway.ORCID 0000-0002-9441-7610
Espen Sønderaal BækkevoldDepartment of Pathology, Oslo University Hospital-Rikshospitalet, Oslo 0372, Norway.ORCID 0000-0002-5890-9108
Frode Lars JahnsenDepartment of Pathology, Institute of Clinical Medicine, University of Oslo, Oslo 0372, Norway.ORCID 0000-0003-3843-7171
Diana DomanskaDepartment of Pathology, Oslo University Hospital-Rikshospitalet, Oslo 0372, Norway.ORCID 0000-0002-6051-1289
Oslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSingle-cell RNA sequencing (scRNA-seq) provides high-resolution transcriptome data to understand the heterogeneity of cell populations at the single-cell level. The analysis of scRNA-seq data requires the utilization of numerous computational tools. However, nonexpert users usually experience installation issues, a lack of critical functionality or batch analysis modes, and the steep learning curves of existing pipelines.

resultsWe have developed cellsnake, a comprehensive, reproducible, and accessible single-cell data analysis workflow, to overcome these problems. Cellsnake offers advanced features for standard users and facilitates downstream analyses in both R and Python environments. It is also designed for easy integration into existing workflows, allowing for rapid analyses of multiple samples.

conclusionAs an open-source tool, cellsnake is accessible through Bioconda, PyPi, Docker, and GitHub, making it a cost-effective and user-friendly option for researchers. By using cellsnake, researchers can streamline the analysis of scRNA-seq data and gain insights into the complex biology of single cells.

Indexed as

SoftwareTranscriptomeGene Expression ProfilingRNASequence Analysis, RNASingle-Cell AnalysisWorkflowRNAmicrobiomeRNA-seqscRNASeuratsingle-cellsnakemakeworkflow

Identifiers

PMID37889009
PMCPMC10603768
OpenAlexW4387965080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.