Evidence map›Paper›PMID 37888754›Full record

ReviewInternational journal of molecular medicine2023

Role of dendritic cell‑derived exosomes in allergic rhinitis (Review).

Chenglin Kang, Haipeng He, Peng Liu, Yue Liu, Xiaomei Li, Jin Zhang, Hong Ran, Xianhai Zeng, Hailiang Zhao, Jiangqi Liu and 1 more

Abstract readReview
In one paragraph

Review in International journal of molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Clinical Applications of Extracellular Vesicles: Promises and Pitfalls.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Exosomes: a promising avenue for cancer diagnosis beyond treatment.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chenglin KangDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.
Haipeng HeDepartment of Otolaryngology, Longgang ENT Hospital and Shenzhen Key Laboratory of ENT, Institute of ENT Shenzhen, Shenzhen, Guangdong 518172, P.R. China.
Peng LiuDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.
Yue LiuDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.
Xiaomei LiDepartment of Otolaryngology, Second People's Hospital of Gansu Province, Lanzhou, Gansu 730000, P.R. China.
Jin ZhangDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.
Hong RanDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.
Xianhai ZengDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.
Hailiang ZhaoDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.
Jiangqi LiuDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.
Shuqi QiuDepartment of Graduate and Scientific Research, Zunyi Medical University Zhuhai Campus, Zhuhai, Guangdong 519041, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) is a common pathological condition in otorhinolaryngology. Its prevalence has been increasing worldwide and is becoming a major burden to the world population. Dendritic cells (DCs) are typically activated and matured after capturing, phagocytosing, and processing allergens during the immunopathogenesis of AR. In addition, the process of DC activation and maturation is accompanied by the production of exosomes, which are cell‑derived extracellular vesicles (EVs) that can carry proteins, lipids, nucleic acids, and other cargoes involved in intercellular communication and material transfer. In particular, DC‑derived exosomes (Dex) can participate in allergic immune responses, where the biological substances carried by them can have potentially important implications for both the pathogenesis and treatment of AR. Dex can also be exploited to carry anti‑allergy agents to effectively treat AR. This provides a novel method to explore the pathogenesis of and treatment strategies for AR further. Therefore, the present review focuses on the origin, composition, function, and biological characteristics of DCs, exosomes, and Dex, in addition to the possible relationship between Dex and AR.

Indexed as

ExosomesExtracellular VesiclesRhinitis, AllergicAllergensDendritic CellsHumansAllergensallergic rhinitisdendritic cellsexosomesextracellular vesiclesintercellular communication

Identifiers

PMID37888754
PMCPMC10635688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.