Evidence map›Paper›PMID 37888690›Full record

ArticleToxics2023

Potential Involvement of Oxidative Stress, Apoptosis and Proinflammation in Ipconazole-Induced Cytotoxicity in Human Endothelial-like Cells.

Iris Ruiz-Yance, Junior Siguas, Brandy Bardales, Ingrid Robles-Castañeda, Karen Cordova, Alina Ypushima, Esteban Estela-Villar, Carlos Quintana-Criollo, Darwin Estacio, José-Luis Rodríguez

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Iris Ruiz-YanceAgroforestry Department, Universidad Nacional Intercultural de la Amazonia, Pucallpa 25004, Peru.
Junior SiguasAnimal Physiology Department, Universidad Nacional Mayor de San Marcos, Lima 15021, Peru.
Brandy BardalesAgroforestry Department, Universidad Nacional Intercultural de la Amazonia, Pucallpa 25004, Peru.
Ingrid Robles-CastañedaAgroforestry Department, Universidad Nacional Intercultural de la Amazonia, Pucallpa 25004, Peru.
Karen CordovaAgroforestry Department, Universidad Nacional Intercultural de la Amazonia, Pucallpa 25004, Peru.
Alina YpushimaAgroforestry Department, Universidad Nacional Intercultural de la Amazonia, Pucallpa 25004, Peru.
Esteban Estela-VillarAgroforestry Department, Universidad Nacional Intercultural de la Amazonia, Pucallpa 25004, Peru.
Carlos Quintana-CriolloAgroforestry Department, Universidad Nacional Intercultural de la Amazonia, Pucallpa 25004, Peru.
Darwin EstacioAgroforestry Department, Universidad Nacional Intercultural de la Amazonia, Pucallpa 25004, Peru.
José-Luis RodríguezPharmacology and Toxicology Department, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-3962-2101
Universidad Nacional Intercultural de la Amazonía · PENational University of San Marcos · PEUniversidad Complutense de Madrid · ES

Funding

National University of San Marcos PCONFIGI A23080521Universidad Nacional Intercultural de la Amazonía VPI funding
6 · The paper itself

Abstract

Triazole fungicides are widely used in the world, mainly in agriculture, but their abuse and possible toxic effects are being reported in some in vivo and in vitro studies that have demonstrated their danger to human health. This in vitro study evaluated the cytotoxicity, oxidative stress and proinflammation of EA.hy926 endothelial cells in response to ipconazole exposure. Using the MTT assay, ipconazole was found to produce a dose-dependent reduction (***

Indexed as

cytotoxicityEA.hy926ipconazole fungicideoxidative stressproinflammation

Identifiers

PMID37888690
PMCPMC10610737
OpenAlexW4387364333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.