Evidence map›Paper›PMID 37888547›Full record

ArticleVeterinary sciences2023

The Synergic Role of Emerging and Endemic Swine Virus in the Porcine Respiratory Disease Complex: Pathological and Biomolecular Analysis.

Giovanni Pietro Burrai, Salwa Hawko, Silvia Dei Giudici, Marta Polinas, Pier Paolo Angioi, Lorena Mura, Alberto Alberti, Chadi Hosri, Georges Hassoun, Annalisa Oggiano and 1 more

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Giovanni Pietro BurraiDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0001-7696-7478
Salwa HawkoDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Silvia Dei GiudiciDepartment of Animal Health, Istituto Zooprofilattico Sperimentale della Sardegna, 07100 Sassari, Italy.ORCID 0000-0003-1803-4666
Marta PolinasDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
Pier Paolo AngioiDepartment of Animal Health, Istituto Zooprofilattico Sperimentale della Sardegna, 07100 Sassari, Italy.
Lorena MuraDepartment of Animal Health, Istituto Zooprofilattico Sperimentale della Sardegna, 07100 Sassari, Italy.
Alberto AlbertiDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-1708-9473
Chadi HosriDepartment of Veterinary Medicine, Faculty of Agricultural Sciences and Veterinary Medicine, Lebanese University, Beirut 1487, Lebanon.ORCID 0000-0001-6015-5395
Georges HassounDepartment of Veterinary Medicine, Faculty of Agricultural Sciences and Veterinary Medicine, Lebanese University, Beirut 1487, Lebanon.
Annalisa OggianoDepartment of Animal Health, Istituto Zooprofilattico Sperimentale della Sardegna, 07100 Sassari, Italy.ORCID 0000-0002-3167-0942
Elisabetta AntuofermoDepartment of Veterinary Medicine, University of Sassari, 07100 Sassari, Italy.
University of Sassari · ITIstituto Zooprofilattico Sperimentale della Sardegna · ITLebanese University · LB

Funding

This research was supported by the Italian Ministry of Health (Grant IZS N° SA 06/21 RC), by the DM 737/2021 risorse 2021-2022, Finanziato dall'Unione europea - NextGenerationEU and by the University of Sassari (Fondo di Ateneo per la Ricerca 2020). Grant IZS N° SA 06/21 RC, DM 737/2021 risorse 2021-2022, Finanziato dall'Unione europea - NextGenerationEU, Fondo di Ateneo per la Ricerca 2020
6 · The paper itself

Abstract

Porcine respiratory disease complex (PRDC) represents a significant threat to the swine industry, causing economic losses in pigs worldwide. Recently, beyond the endemic viruses PRRSV and PCV2, emerging viruses such as TTSuV, PCV3, and PPV2, have been associated with PRDC, but their role remains unclear. This study investigates the presence of PCV2 and PRRSV and emerging viruses (PCV3, TTSuV, and PPV2) in the lungs of swine belonging to different age groups by histopathology and real-time PCR. The prevalent lung lesion was interstitial pneumonia with increased severity in post-weaning pigs. PRRSV was detected in 33% of piglets' lungs and in 20% of adults and post-weaning pigs with high Ct, while PCV2 was found in 100% of adult pigs, 33% of post-weaning pigs, and 22% of piglets, with low Ct in post-weaning pigs. PCV3 was present in all categories and coexisted with other viruses. TTSuV was detected in all swine in combination with other viruses, possibly influencing the disease dynamics, while PPV2 was detected in 100% of adults' and 90% of piglets' lungs. The detection of TTSuV, PCV3, and PPV2 in affected pigs prioritizes the need for comprehensive approaches in implementing appropriate control measures and minimizing economic losses associated with PRDC.

Indexed as

emerging virusespathologyRT-PCRswine

Identifiers

PMID37888547
PMCPMC10611356
OpenAlexW4387118933

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.