Evidence map›Paper›PMID 37888270›Full record

ArticleJournal of fungi (Basel, Switzerland)2023

Differential Transcriptional Responses of Human Granulocytes to Fungal Infection with

Tilman E Klassert, Martin Hölzer, Cristina Zubiria-Barrera, Julia Bethge, Esther Klaile, Mario M Müller, Manja Marz, Hortense Slevogt

Abstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tilman E KlassertRespiratory Infection Dynamics, Helmholtz Centre for Infection Research-HZI Braunschweig, 38124 Braunschweig, Germany.ORCID 0000-0002-4502-5450
Martin HölzerMethodology and Research Infrastructure, Genome Competence Center (MF1), Robert Koch Institute, 13353 Berlin, Germany.
Cristina Zubiria-BarreraRespiratory Infection Dynamics, Helmholtz Centre for Infection Research-HZI Braunschweig, 38124 Braunschweig, Germany.
Julia BethgeZIK Septomics, Host Septomics, Jena University Hospital, 07747 Jena, Germany.
Esther KlaileZIK Septomics, Host Septomics, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0001-7389-6862
Mario M MüllerZIK Septomics, Host Septomics, Jena University Hospital, 07747 Jena, Germany.ORCID 0000-0002-1898-5691
Manja MarzRNA Bioinformatics and High Throughput Analysis, Friedrich Schiller University Jena, 07743 Jena, Germany.ORCID 0000-0003-4783-8823
Hortense SlevogtRespiratory Infection Dynamics, Helmholtz Centre for Infection Research-HZI Braunschweig, 38124 Braunschweig, Germany.

Funding

Deutsche Forschungsgemeinschaft 210879364 and 390874280
6 · The paper itself

Abstract

Neutrophils are critical phagocytic cells in innate immunity, playing a significant role in defending against invasive fungal pathogens. This study aimed to explore the transcriptional activation of human neutrophils in response to different fungal pathogens, including

Indexed as

AspergillusCandidaneutrophilsRNAseq

Identifiers

PMID37888270
PMCPMC10607568

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.