ReviewJournal of personalized medicine2023
Pain Assessment Using the Analgesia Nociception Index (ANI) in Patients Undergoing General Anesthesia: A Systematic Review and Meta-Analysis.
Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Trial
- Preventing Postoperative Catheter-Related Bladder Discomfort (CRBD) with Bladder Irrigation Using 0.05% Lidocaine Saline Solution: Monitoring with Analgesia Nociception Index (ANI) after Transurethral Surgery.Medicina (Kaunas, Lithuania) · 2024Trial
- Beyond the Numerical Rating Scale: Comprehensive Pain Assessment in the Post-Anesthesia Care Unit.Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses · 2026Article
- Effect of preoperative β-blocker use on Analgesia-Nociception Index during laparoscopic cholecystectomy.Journal of clinical monitoring and computing · 2026Observational
- Nociception index-monitored extubation is associated with improved hemodynamic stability and recovery efficiency in the post-anesthesia care unit: a single-center randomized controlled trial.Journal of clinical monitoring and computing · 2026Article
- Depth of anesthesia monitoring: Current evidence, clinical impact, and future directions.The Journal of international medical research · 2026Review
- Plasma concentration of dexmedetomidine combined with fixed remifentanil for nociceptive and hemodynamic control during skull pin fixation.Scientific reports · 2026Article
- Dexmedetomidine attenuates nociceptive responses compared with propofol during intravenous sedation for dental surgery: a prospective observational study.Journal of dental anesthesia and pain medicine · 2026Article
- Pupillometry as a Novel Tool for Pain Monitoring: Evaluating the Antinociceptive Effect of Intravenous Lidocaine During Orotracheal Intubation.Journal of clinical medicine · 2026Article
- Perioperative Sympathetic Blockade: Mechanisms and Clinical Advances in Sensory Processing Modulation - A Narrative Review.Journal of pain research · 2026Review
- Postoperative pain management in children.Frontiers in pediatrics · 2026Review
- Objective monitoring of acute pain and nociception in anaesthesia and intensive care: evidence and applications.Anaesthesiology intensive therapy · 2025Review
- The Role of Artificial Intelligence in Anesthesia Monitoring and Surveillance.Anesthesiology clinics · 2025Review
- Variations of SPI during outpatient laparoscopic cholecystectomy without muscle relaxants using ANI-guided remifentanil.Journal of clinical monitoring and computing · 2025Observational
- Integrating Telemedical Supervision, Responder Apps, and Data-Driven Triage: The RuralRescue Model of Personalized Emergency Care.Journal of personalized medicine · 2025Article
- Pain assessment using the Analgesia Nociception Index in patients undergoing sedation: a systematic review and meta-analysis.The Korean journal of pain · 2025Article
- The Analgesia Nociception Index's Performance During Remimazolam-Based General Anesthesia: A Prospective Observational Study.Medicina (Kaunas, Lithuania) · 2025Observational
- Analgesia Nociception Index Monitoring in Management of Perioperative Analgesia in Total Knee Arthroplasty Surgeries with Femoral Nerve Block.Medicina (Kaunas, Lithuania) · 2025Article
- Physiological framework for non-invasive detection and objective nociception activity in communicative patients: a pilot case study.Frontiers in physiology · 2025Article
- Epidural, Inadvertent Subdural, and Combined Epidural-Subdural Anesthesia in Lumbar Spine Surgery: A Retrospective Analysis.Journal of personalized medicine · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The analgesia nociception index (ANI) has emerged as a potential measurement for objective pain assessment during general anesthesia. This systematic review and meta-analysis aimed to evaluate the accuracy and effectiveness of ANI in assessing intra- and post-operative pain in patients undergoing general anesthesia. We conducted a comprehensive search of Ovid-MEDLINE, Ovid-EMBASE, Cochrane Central Register of Controlled Trials, Google Scholar, public clinical trial databases (ClinicalTrials and Clinical Research Information Service), and OpenSIGLE to identify relevant studies published prior to May 2023 and included studies that evaluated the accuracy and effectiveness of ANI for intra- or post-operative pain assessment during general anesthesia. Among the 962 studies identified, 30 met the eligibility criteria and were included in the systematic review, and 17 were included in the meta-analysis. For predicting intra-operative pain, pooled sensitivity, specificity, diagnostic odds ratio (DOR), and area under curve of ANI were 0.81 (95% confidence interval [CI] = 0.79-0.83; I
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