Evidence map›Paper›PMID 37888046›Full record

ArticleJournal of personalized medicine2023

Inflammatory Biomarkers and Blood Physical Property Transformations Following On-Pump Coronary Artery Bypass Graft Surgery.

Po-Shun Hsu, Jia-Lin Chen, Shih-Ying Sung, Yi-Ting Tsai, Chih-Yuan Lin, Yi-Fan Wu, Chien-Sung Tsai

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Po-Shun HsuDivision of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Jia-Lin ChenDepartment of Anesthesia, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.ORCID 0000-0002-7519-0545
Shih-Ying SungDivision of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Yi-Ting TsaiDivision of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Chih-Yuan LinDivision of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Yi-Fan WuSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110301, Taiwan.ORCID 0000-0001-8872-6014
Chien-Sung TsaiDivision of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Tri-Service General Hospital · TWInstitute of Physics, Academia Sinica · TW

Funding

Mathematical models for rotary protein motors driven by membrane potentialR01GM110066 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MANDADAPU, KRANTHI KIRAN · 2015 to 2017
$634k
Ministry of Science and Technology MOST 111-2314-B-016 -008Tri-service General Hospital, National Defense Medical Center TSGH-D-110066, TSGH-D-111049, TSGH-A-112007, TSGH-D-112175
6 · The paper itself

Abstract

objectiveThis study aimed to compare the hemorheological and inflammatory changes before and after coronary artery bypass graft (CABG) surgery, as factors such as hypothermia, hemodilution, transfusion, and other variables affect blood viscosity and inflammation during the procedure.

methodsA total of 25 patients who underwent CABG surgery were enrolled in this study. Whole blood was collected just before the CABG (D

resultsCompared with the baseline values, the PV significantly increased after 5 days. WBV showed a significant increase on day 2 and after 5 days. The WBV and fibrinogen were significantly correlated on day 2 and day 5 but not before surgery. Inflammatory markers such as CRP, WBC, platelets, and fibrinogen also demonstrated notable changes in relation to the hemorheological alterations.

conclusionsThis study highlights the crucial finding that hyperviscosity, characterized by elevated PV and WBV, persists for almost one week after on-pump CABG surgery. Understanding the interplay between inflammation and hemorheological properties during the postoperative period is crucial for optimizing patient care. Future research should focus on exploring the underlying mechanisms and potential therapeutic interventions to mitigate the impact of inflammation on blood viscosity and improve patient outcomes following CABG surgery.

Indexed as

cardiopulmonary bypasshemorheologyinflammationon-pump coronary artery bypass graft

Identifiers

PMID37888046
PMCPMC10607935
OpenAlexW4387054157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.