ReviewJournal of personalized medicine2023
Intraoperative Neuromonitoring Does Not Reduce the Risk of Temporary and Definitive Recurrent Laryngeal Nerve Damage during Thyroid Surgery: A Systematic Review and Meta-Analysis of Endoscopic Findings from 73,325 Nerves at Risk.
Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Article
- [Etiology, Evaluation and Comprehensive Management of Hoarseness after Lung Cancer Surgery].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2026Review
- Active surveillance in thyroid cancer: a paradigm shift requiring critical appraisal and caution.European journal of nuclear medicine and molecular imaging · 2026Article
- Article
- Use of intraoperative neuromonitoring in robotic thyroidectomy: a systematic review of recurrent laryngeal nerve outcomes.Annals of medicine and surgery (2012) · 2026Article
- Ultrasonography of the recurrent laryngeal nerve in thyroid cancer: advances in clinical application and research progress.Frontiers in oncology · 2026Review
- Glass-blowing, brass-playing, and other laryngocele etiologies: Fact or fiction? A systematic literature review.World journal of otorhinolaryngology - head and neck surgery · 2025Review
- Surgical Timing in Thyroid Cancer with Lateral Neck Metastases: Delayed Versus Contemporary Lateral Neck Dissection.Cancers · 2025Article
- Can early postoperative ultrasound replace routinary flexible laryngoscopy after neuromonitoring-assisted thyroid surgery?Updates in surgery · 2025Article
- Thyroid surgery outcomes in a 4-year series with intraoperative neuromonitoring: a retrospective cohort study.Gland surgery · 2025Article
- Utility of continuous vagal neuromonitoring in thyroid and parathyroid gland surgery: a retrospective study of 500 cases.Gland surgery · 2025Article
- Progress and Outcomes of Intraoperative Nerve Monitoring During Thyroidectomy.JAMA otolaryngology-- head & neck surgery · 2025Article
- Anatomical recognition artificial intelligence for identifying the recurrent laryngeal nerve during endoscopic thyroid surgery: A single-center feasibility study.Laryngoscope investigative otolaryngology · 2024Article
- Pediatric Odontogenic Sinusitis: A Systematic Review.Journal of clinical medicine · 2024Review
Corrections and comments
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Authors and funding
16 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile intraoperative neuromonitoring (IONM) helps the early identification of recurrent laryngeal nerve (RLN) damage, IONM's role in RLN damage prevention is not defined, given the lack of large studies on the subject.
methodsIn a PRISMA-compliant framework, all original thyroid surgery prospective studies providing early postoperative endoscopic data for all patients were pooled in a random-effects meta-analysis. We compared the temporary (and definitive where available) RLN damage rates according to IONM use and IONM type (intermittent, I-IONM, or continuous, C-IONM).
resultsWe identified 2358 temporary and 257 definitive RLN injuries in, respectively, 73,325 and 66,476 nerves at risk. The pooled temporary and definitive RLN injury rates were, respectively, 3.15% and 0.422% considering all procedures, 3.29% and 0.409% in cases using IONM, and 3.16% and 0.463 in cases not using IONM. I-IONM and C-IONM, respectively, showed a pooled temporary RLN injury rate of 2.48% and 2.913% and a pooled definitive injury rate of 0.395% and 0.4%. All pooled rates had largely overlapping 95% confidence intervals.
conclusionsOur data suggest that IONM does not affect the temporary or definitive RLN injury rate following thyroidectomy, though its use can be advised in selected cases and for bilateral palsy prevention.
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