Evidence map›Paper›PMID 37887785›Full record

ReviewPathogens (Basel, Switzerland)2023

The Bacterial Oral Microbiome in Children with Congenital Heart Disease: An Extensive Review.

Maria Hofmann, Nelly Schulz-Weidner, Norbert Krämer, Torsten Hain

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Low-Cost Protocol for Quantitative Measurement ofLife (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Oral Cavity Microbiome Impact on Respiratory Infections Among Children.Pediatric health, medicine and therapeutics · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maria HofmannDental Clinic-Department of Paediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany.
Nelly Schulz-WeidnerDental Clinic-Department of Paediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany.ORCID 0000-0003-4562-8232
Norbert KrämerDental Clinic-Department of Paediatric Dentistry, Justus Liebig University, Schlangenzahl 14, 35392 Giessen, Germany.
Torsten HainInstitute of Medical Microbiology, Justus Liebig University, Schubertstrasse 81, 35392 Giessen, Germany.
Justus-Liebig-Universität Gießen · DE

Funding

JLU CAREER Program of the Faculty of Medicine at Justus Liebig University Giessen DFG grant number GU 405/14-1
6 · The paper itself

Abstract

Children with congenital heart disease have poorer oral health compared with healthy children. Oral diseases, such as dental caries and gingivitis, are associated with the oral microbiome. The objective of this review was to find evidence of differences in the bacterial colonization of the oral cavity of children with congenital heart disease (CHD) versus healthy children. A literature review was conducted according to predetermined criteria, including the need for controlled clinical trials. Half of the 14 studies that met the inclusion criteria reported significant differences in bacterial colonization in children with congenital heart disease. A variety of influencing factors were discussed. There is some evidence for alterations in the oral microflora as a result of physiopathological and treatment-related factors in children with CHD, but additional research is required to validate these findings.

Indexed as

childrencongenital heart diseaseoral microbiome

Identifiers

PMID37887785
PMCPMC10610089
OpenAlexW4387843552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.