Evidence map›Paper›PMID 37887757›Full record

ArticlePathogens (Basel, Switzerland)2023

Natural Killer Repertoire Restoration in TB/HIV Co-Infected Individuals Experienced an Immune Reconstitution Syndrome (CAMELIA Trial, ANRS 12153).

Polidy Pean, Yoann Madec, Eric Nerrienet, Laurence Borand, Didier Laureillard, Marcelo Fernandez, Olivier Marcy, Daniel Scott-Algara, CAMELIA Study Team

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Tuberculosis treatment and cytotoxic immune signatures: a longitudinal study.Journal of clinical tuberculosis and other mycobacterial diseases · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Polidy PeanImmunology Unit, Institute Pasteur du Cambodge, Phnom Pen 12000, Cambodia.ORCID 0000-0002-2252-9277
Yoann MadecEpidemiology of Emerging Diseases, Institut Pasteur, Université de Paris, 75000 Paris, France.ORCID 0000-0002-6201-1261
Eric NerrienetInstitut Pasteur, 75000 Paris, France.
Laurence BorandClinical Research Team, Epidemiology and Public Health Unit, Institut Pasteur du Cambodge, Phom Penh 12000, Cambodia.
Didier LaureillardInfectious and Tropical Diseases Department, University Hospital, 30900 Nimes, France.ORCID 0000-0002-0104-9047
Marcelo FernandezMédecins Sans Frontières, 1200 Geneva, Switzerland.
Olivier MarcyResearch Institute for Sustainable Development (IRD) EMR 271, National Institute for Health and Medical Research (INSERM) UMR 1219, University of Bordeaux, 33000 Bordeaux, France.ORCID 0000-0003-3350-112X
Daniel Scott-AlgaraUnité de Biologie Cellulaire et Lymphocytes, Institut Pasteur, 75000 Paris, France.ORCID 0000-0003-1851-503X
CAMELIA Study Team
Institut Pasteur · FRInstitut Pasteur du Cambodge · KHJohns Hopkins University · USMédecins Sans Frontières · CHUniversité de Bordeaux · FRUniversité de Nîmes · FR

Funding

ANRS 12153
6 · The paper itself

Abstract

IRIS is a common complication in HIV-infected patients treated for tuberculosis (TB) and cART. Our aim was to evaluate NK cell reconstitution in HIV-infected patients with TB-IRIS compared to those without IRIS. 147 HIV-infected patients with TB from the CAMELIA trial were enrolled. HIV+TB+ patients were followed for 32 weeks. The NK cell repertoire was assessed in whole blood at different time points. As CAMELIA has two arms (early and late cART initiation), we analysed them separately. At enrolment, individuals had low CD4 cell counts (27 cells/mm

Indexed as

antiretroviral treatmentHIVimmune reconstitutionimmune reconstitution inflammatory syndromeNK cellstuberculosis

Identifiers

PMID37887757
PMCPMC10610037
OpenAlexW4387618262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.