Evidence map›Paper›PMID 37887627›Full record

ReviewBiomimetics (Basel, Switzerland)2023

Improving Pancreatic Cyst Management: Artificial Intelligence-Powered Prediction of Advanced Neoplasms through Endoscopic Ultrasound-Guided Confocal Endomicroscopy.

Joanna Jiang, Wei-Lun Chao, Troy Cao, Stacey Culp, Bertrand Napoléon, Samer El-Dika, Jorge D Machicado, Rahul Pannala, Shaffer Mok, Anjuli K Luthra and 3 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Biomimetics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07543263 (An Artificial Intelligence System for Multimodal, Multi-class Diagnosis of Pancreatic Cystic Lesions Based on Endoscopic Ultrasonography), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07543263 recruitingnot on this mapstarted 2026, after this paper: background citation

An Artificial Intelligence System for Multimodal, Multi-class Diagnosis of Pancreatic Cystic Lesions Based on Endoscopic Ultrasonography

TypeobservationalSponsorQilu Hospital of Shandong UniversityRan2026 to 2028Enrolled176ConditionsPancreatic Cystic Lesion (PCL)ArmsiEUS-PCL(intelligent endoscopic ultrasound system- pancreatic cystic lesion)
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Endoscopic management of pancreatic cystic neoplasms.World journal of gastrointestinal oncology · 2025
    Review
  3. Article
  4. Current Endoscopic and Surgical Management of Pancreatic Cystic Lesions: A Comprehensive Review.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
    Review
  5. Review
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 2 countries.

Joanna JiangDivision of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Wei-Lun ChaoDepartment of Computer Science and Engineering, College of Engineering, The Ohio State University, Columbus, OH 43210, USA.
Troy CaoCollege of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Stacey CulpDepartment of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-9180-6426
Bertrand NapoléonDepartment of Gastroenterology, Jean Mermoz Private Hospital, 69008 Lyon, France.
Samer El-DikaDivision of Gastroenterology and Hepatology, Stanford University, Stanford, CA 94305, USA.
Jorge D MachicadoDivision of Gastroenterology, University of Michigan, Ann Arbor, MI 48109, USA.
Rahul PannalaDivision of Gastroenterology and Hepatology, Mayo Clinic Arizona, Phoenix, AZ 85054, USA.
Shaffer MokDivision of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Anjuli K LuthraDivision of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Venkata S AkshintalaDivision of Gastroenterology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
Thiruvengadam MunirajDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.
Somashekar G KrishnaDivision of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.ORCID 0000-0001-5748-7890
The Ohio State University · USMoffitt Cancer Center · USThe Ohio State University Wexner Medical Center · USHôpital Privé Jean Mermo · FRJohns Hopkins University · USStanford University · USUniversity of Michigan · USWinnMed · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Endoscopic Ultrasound-guided In Vivo Confocal Laser Endomicroscopy as an Imaging Biomarker for the Accurate Risk Stratification of Intraductal Papillary Mucinous NeoplasmsR01CA279965 · NCI · OHIO STATE UNIVERSITY · PI Somashekar G. Krishna · 2023 to 2026
$1.7M
NCATS NIH HHS UL1 TR001863NCI NIH HHS R01 CA279965
6 · The paper itself

Abstract

Despite the increasing rate of detection of incidental pancreatic cystic lesions (PCLs), current standard-of-care methods for their diagnosis and risk stratification remain inadequate. Intraductal papillary mucinous neoplasms (IPMNs) are the most prevalent PCLs. The existing modalities, including endoscopic ultrasound and cyst fluid analysis, only achieve accuracy rates of 65-75% in identifying carcinoma or high-grade dysplasia in IPMNs. Furthermore, surgical resection of PCLs reveals that up to half exhibit only low-grade dysplastic changes or benign neoplasms. To reduce unnecessary and high-risk pancreatic surgeries, more precise diagnostic techniques are necessary. A promising approach involves integrating existing data, such as clinical features, cyst morphology, and data from cyst fluid analysis, with confocal endomicroscopy and radiomics to enhance the prediction of advanced neoplasms in PCLs. Artificial intelligence and machine learning modalities can play a crucial role in achieving this goal. In this review, we explore current and future techniques to leverage these advanced technologies to improve diagnostic accuracy in the context of PCLs.

Indexed as

artificial intelligenceendomicroscopyendoscopic ultrasoundendoscopyEUS-nCLEIPMNmachine learningpancreatic cancerpancreatic cysts

Identifiers

PMID37887627
PMCPMC10604893
OpenAlexW4387776274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.