Evidence map›Paper›PMID 37887567›Full record

ReviewCurrent oncology (Toronto, Ont.)2023

Local Control Following Stereotactic Body Radiation Therapy for Liver Oligometastases: Lessons from a Quarter Century.

Sara Mheid, Stefan Allen, Sylvia S W Ng, William A Hall, Nina N Sanford, Todd A Aguilera, Ahmed M Elamir, Rana Bahij, Martijn P W Intven, Ganesh Radhakrishna and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 9 countries.

Sara MheidDepartment of Radiation Oncology, University of Toronto, Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.
Stefan AllenDepartment of Radiation Oncology, Dalhousie University, Nova Scotia Health, Halifax, NS B3H 4R2, Canada.
Sylvia S W NgDepartment of Radiation Oncology, University of Toronto, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
William A HallDepartment of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Nina N SanfordDepartment of Radiation Oncology, University of Texas Southwestern, Dallas, TX 75235, USA.
Todd A AguileraDepartment of Radiation Oncology, University of Texas Southwestern, Dallas, TX 75235, USA.
Ahmed M ElamirDepartment of Radiation Oncology, University of Texas Southwestern, Dallas, TX 75235, USA.
Rana BahijDepartment of Oncology, Odense University Hospital, 5000 Odense, Denmark.
Martijn P W IntvenDepartment of Radiotherapy, Division Imaging and Oncology, University Medical Centre, 3584 CX Utrecht, The Netherlands.
Ganesh RadhakrishnaDepartment of Radiotherapy, The Christie NHS Foundation Trust, Manchester M20 4BX, UK.
Issa MohamadDepartment of Radiation Oncology, King Hussein Cancer Center, Amman 11941, Jordan.ORCID 0000-0003-0153-9131
Jeremy De LeonGenesisCare, Alexandria, NSW 2015, Australia.
Hendrick TanDepartment of Radiation Oncology, Fiona Stanley Hospital, Perth, WA 6150, Australia.
Shirley LewisDepartment of Radiotherapy and Oncology, Manipal Comprehensive Cancer Care Centre, Kasturba Medical College, Manipal Academy of Higher Education, Manipal 576104, India.ORCID 0000-0001-5306-1649
Cihan GaniDepartment of Radiation Oncology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-0242-9428
Teo StanecuDepartment of Radiation Oncology, University of Toronto, Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.
Veronica Dell'AcquaMedical Affairs and Clinical Research, Linac-Based RT, Elekta Milan, 20864 Lombardy, Italy.
Ali HosniDepartment of Radiation Oncology, University of Toronto, Princess Margaret Cancer Centre, Toronto, ON M5G 2M9, Canada.
The University of Texas Southwestern Medical Center · USUniversity of Toronto · CAAustralian and New Zealand Intensive Care Society · AUDalhousie University · CAGenesis HealthCare · USKing Hussein Cancer Center · JOManipal Academy of Higher Education · INMedical College of Wisconsin · USOdense University Hospital · DKSunnybrook Health Science Centre · CAThe Christie NHS Foundation Trust · GBUniversity Children's Hospital Tübingen · DEUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The utilization of stereotactic body radiation therapy for the treatment of liver metastasis has been widely studied and has demonstrated favorable local control outcomes. However, several predictive factors play a crucial role in the efficacy of stereotactic body radiation therapy, such as the number and size (volume) of metastatic liver lesions, the primary tumor site (histology), molecular biomarkers (e.g., KRAS and TP53 mutation), the use of systemic therapy prior to SBRT, the radiation dose, and the use of advanced technology and organ motion management during SBRT. These prognostic factors need to be considered when clinical trials are designed to evaluate the efficacy of SBRT for liver metastases.

Indexed as

Liver NeoplasmsRadiosurgeryHumansliveroligometastasesSBRT

Identifiers

PMID37887567
PMCPMC10605011
OpenAlexW4387774191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.