Evidence map›Paper›PMID 37887563›Full record

ArticleCurrent oncology (Toronto, Ont.)2023

Safety and Efficacy of Hepatic Artery Embolization in Heavily Treated Patients with Intrahepatic Cholangiocarcinoma: Analysis of Clinicopathological and Radiographic Parameters Associated with Better Overall Survival.

Sara Velayati, Ahmed Elsakka, Ken Zhao, Joseph P Erinjeri, Brett Marinelli, Mohamed Soliman, Olivier Chevallier, Etay Ziv, Lynn A Brody, Constantinos T Sofocleous and 8 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Sara VelayatiDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Ahmed ElsakkaDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Ken ZhaoDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Joseph P ErinjeriDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Brett MarinelliDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Mohamed SolimanDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Olivier ChevallierDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0002-3888-3174
Etay ZivDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Lynn A BrodyDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Constantinos T SofocleousDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.ORCID 0000-0002-3142-1399
Stephen B SolomonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
James J HardingDepartment of Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Ghassan K Abou-AlfaDepartment of Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Michael I D'AngelicaDepartment of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Alice C WeiDepartment of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Peter T KinghamDepartment of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
William R JarnaginDepartment of Surgical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Hooman YarmohammadiDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Improving Outcome in Patients with Advanced Intrahepatic Cholangiocarcinoma: A Randomized Phase II Study of Gemcitabine and Oxaliplatin With or Without Regional Floxuridine (FUDR)U01CA238444 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CERCEK, ANDREA, IACOBUZIO-DONAHUE, CHRISTINE A · 2020 to 2024
$3.3M
Deformation Corrected Image Guided Laparoscopic Liver SurgeryR01EB027498 · NIBIB · VANDERBILT UNIVERSITY · PI JARNAGIN, WILLIAM ROBERT, MIGA, MICHAEL IAN · 2019 to 2022
$2.5M
Optimizing Thermal Ablation for Colon Cancer Liver Metastases: Rapid Tissue Analysis Allowing for Immediate Retreatment; Metabolic Imaging Biomarker Validation; and Predictive Genetic SignaturesR01CA240569 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI SOFOCLEOUS, CONSTANTINOS THASOS · 2019 to 2022
$840k
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA240569NCI NIH HHS U01 CA238444NIBIB NIH HHS R01 EB027498
6 · The paper itself

Abstract

The safety and efficacy of hepatic artery embolization (HAE) in treating intrahepatic cholangiocarcinoma (IHC) was evaluated. Initial treatment response, local tumor progression-free survival (L-PFS), and overall survival (OS) were evaluated in 34 IHC patients treated with HAE. A univariate survival analysis and a multivariate Cox proportional hazard analysis to identify independent factors were carried out. Objective response (OR) at 1-month was 79.4%. Median OS and L-PFS from the time of HAE was 13 (CI = 95%, 7.4-18.5) and 4 months (CI = 95%, 2.09-5.9), respectively. Tumor burden < 25% and increased tumor vascularity on preprocedure imaging and surgical resection prior to embolization were associated with longer OS (

Indexed as

Bile Duct NeoplasmsCholangiocarcinomaBile Ducts, IntrahepaticHepatic ArteryHumansTreatment Outcomehepatic artery embolizationintrahepatic cholangiocarcinomaoverall survivaltumor response

Identifiers

PMID37887563
PMCPMC10605490
OpenAlexW4387774224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.