Evidence map›Paper›PMID 37887537›Full record

ArticleCurrent oncology (Toronto, Ont.)2023

Predictors and Consequences of Cancer and Non-Cancer-Related Pain in Those Diagnosed with Primary and Metastatic Cancers.

Kriti Shah, David A Geller, Samer Tohme, Michael Antoni, Cramer J Kallem, Yoram Vodovotz, Rekha Ramanathan, Raam Naveen, MacKenzie Geroni, LaNita Devine and 5 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Cancer pain.Nature reviews. Disease primers · 2026
    Review
  3. Article
  4. Review
  5. Patient-reported pain severity is associated with shorter survival in older adults with newly diagnosed cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Kriti ShahDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
David A GellerDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Samer TohmeDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Michael AntoniDepartment of Psychology, University of Miami, Coral Gables, FL 33124, USA.
Cramer J KallemDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Yoram VodovotzDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Rekha RamanathanDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Raam NaveenDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
MacKenzie GeroniDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
LaNita DevineDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Aarshati AminDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Gauri J KieferUPMC Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Dan P ZandbergUPMC Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
Vincent ReyesUPMC Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.ORCID 0009-0000-7759-0529
Jennifer L SteelDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
University of Pittsburgh · USUniversity of Pittsburgh Medical Center · USUniversity of Miami · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Palliative care intervention for socioeconomically disadvantaged cancer patientsR01CA196953 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEEL, JENNIFER L. · 2016 to 2020
$3.4M
Biobehavioral pathways linking stress and cancer progressionR01CA176809 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEEL, JENNIFER L. · 2012 to 2014
$1.3M
Comprehensive Electronic Support System for Treatment of Cancer-Related SymptomsK07CA118576 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEEL, JENNIFER L. · 2006 to 2010
$757k
Analysis of the Cytokine-Immunological Model of a Cancer-Related Symptom ClusterR21CA127046 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEEL, JENNIFER L. · 2008 to 2009
$375k
NCATS NIH HHS UL1 TR001857NCI NIH HHS K07 CA118576NCI NIH HHS R01 CA176809NCI NIH HHS R01 CA196953NCI NIH HHS R21 CA127046
6 · The paper itself

Abstract

objectivesThe aims of the study were to (1) describe types of pain in cancer patients, (2) examine the predictors and consequences of pain, (3) investigate the association between type of pain and survival, and (4) examine potential biological mediators of pain and survival.

methodsThis was a secondary analysis of baseline data from patients diagnosed with cancer. Patients answered questionnaires that assessed sociodemographic characteristics, pain, depression, sleep, and fatigue. Blood was collected and cytokine assays were performed. Analysis of variance, Kaplan-Meier, and Cox regression survival analyses were used to test the aims.

resultsOf the 779 patients diagnosed with cancer, the mean age was 63.5 years, 57.8% male, and 90.6% White. Of those who reported pain (total 70.3%), 46.5% stated their pain was cancer-related while 53.5% stated their pain was non-cancer-related. While both cancer and non-cancer-related pain was associated with depressive symptoms, fatigue, and sleep duration, those with cancer-related pain had significantly higher rates of depressive symptoms (F(1,516) = 21.217,

conclusionWhile nearly half of the pain reported was cancer-related, both types of pain resulted in greater symptom burden, but only cancer-related pain was associated with survival.

Indexed as

Cancer PainNeoplasmsNeoplasms, Second PrimaryDepressionFatigueFemaleHumansMaleMiddle AgedPaincancercytokinesdepressionfatigueinflammationpainsleep

Identifiers

PMID37887537
PMCPMC10605887
OpenAlexW4387132549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.