Evidence map›Paper›PMID 37887420›Full record

ArticleMetabolites2023

Linking Clinical Blood Metabogram and Gut Microbiota.

Petr G Lokhov, Elena E Balashova, Dmitry L Maslov, Oxana P Trifonova, Andrey V Lisitsa, Yulia M Markova, Valentina V Stetsenko, Anna S Polyanina, Svetlana A Sheveleva, Khaider K Sharafetdinov and 3 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Pathological Alterations in Human Blood Microbiome-An Updated Review.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Petr G LokhovInstitute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.ORCID 0000-0002-0730-1725
Elena E BalashovaInstitute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.ORCID 0000-0002-5314-5727
Dmitry L MaslovInstitute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.ORCID 0000-0003-3003-7595
Oxana P TrifonovaInstitute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.ORCID 0000-0002-5803-2529
Andrey V LisitsaInstitute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.
Yulia M MarkovaFederal State Budgetary Institution of Science, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Ustinsky Passage 2/14, 109240 Moscow, Russia.ORCID 0000-0002-2631-6412
Valentina V StetsenkoFederal State Budgetary Institution of Science, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Ustinsky Passage 2/14, 109240 Moscow, Russia.
Anna S PolyaninaFederal State Budgetary Institution of Science, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Ustinsky Passage 2/14, 109240 Moscow, Russia.ORCID 0000-0002-2766-7716
Svetlana A ShevelevaFederal State Budgetary Institution of Science, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Ustinsky Passage 2/14, 109240 Moscow, Russia.
Khaider K SharafetdinovFederal State Budgetary Institution of Science, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Ustinsky Passage 2/14, 109240 Moscow, Russia.
Dmitry B NikityukFederal State Budgetary Institution of Science, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Ustinsky Passage 2/14, 109240 Moscow, Russia.
Victor A TutelyanFederal State Budgetary Institution of Science, Federal Research Centre of Nutrition, Biotechnology and Food Safety, Ustinsky Passage 2/14, 109240 Moscow, Russia.
Alexander I ArchakovInstitute of Biomedical Chemistry, 10 Building 8, Pogodinskaya Street, 119121 Moscow, Russia.
Federal Research Centre of Nutrition and Biotechnology · RUInstitute of Biomedical Chemistry · RU

Funding

Ministry of Education and Science of the Russian Federation Agreement No. 075-15-2021-933, unique project ID: RF00121X0004
6 · The paper itself

Abstract

Recently, a clinical blood metabogram was developed as a fast, low-cost and reproducible test that allows the implementation of metabolomics in clinical practice. The components of the metabogram are functionally related groups of blood metabolites associated with humoral regulation, the metabolism of lipids, carbohydrates and amines, lipid intake into the organism, and liver function, thereby providing clinically relevant information. It is known that the gut microbiota affects the blood metabolome, and the components of the blood metabolome may affect the composition of the gut microbiota. Therefore, before using the metabogram in the clinic, the link between the metabogram components and the level of gut microorganisms should be established. For this purpose, the metabogram and microbiota data were obtained in this work for the same individuals. Metabograms of blood plasma were obtained by direct mass spectrometry of blood plasma, and the gut microbiome was determined by a culture-based method and real-time polymerase chain reaction (PCR). This study involved healthy volunteers and individuals with varying degrees of deviation in body weight (

Indexed as

bloodclinical blood testclinical metabolomicsdiagnosticsgut microbiomegut microbiotamass spectrometrymetabogrammetabolomicspersonalized metabolomics

Identifiers

PMID37887420
PMCPMC10609303
OpenAlexW4387781120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.