Evidence map›Paper›PMID 37887416›Full record

ArticleMetabolites2023

Identification of the Biosynthetic Gene Cluster of New Piperazic Acid-Containing Lipopeptides with Cytotoxic Activity in the Genome of Marine Streptomyces PHM034.

Ana Ceniceros, Librada Cañedo, Carmen Méndez, Carlos Olano, Carmen Schleissner, Carmen Cuevas, Fernando de la Calle, José A Salas

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ana CenicerosDepartamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain.ORCID 0000-0001-9921-9421
Librada CañedoDrug Discovery Area, PharmaMar S.A. Avda. de los Reyes 1, Colmenar Viejo, 28770 Madrid, Spain.ORCID 0000-0002-1273-4138
Carmen MéndezDepartamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain.ORCID 0000-0003-2729-841X
Carlos OlanoDepartamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain.ORCID 0000-0001-5440-3540
Carmen SchleissnerUnolab Manufacturing, Avenida de las Flores 6, Humanes de Madrid, 28970 Madrid, Spain.
Carmen CuevasDrug Discovery Area, PharmaMar S.A. Avda. de los Reyes 1, Colmenar Viejo, 28770 Madrid, Spain.
Fernando de la CalleDrug Discovery Area, PharmaMar S.A. Avda. de los Reyes 1, Colmenar Viejo, 28770 Madrid, Spain.ORCID 0000-0001-8161-8299
José A SalasDepartamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain.ORCID 0000-0001-6495-3810
Universidad de Oviedo · ESPharmaMar (Spain) · ES

Funding

Ministry of Economy and Competitiveness and the Ministry of Science, Innovation and Uni-versities of Spain RTC-2016-4892-1 (DESPOL) and RTC-2017-6405-1 (MARBIOM) respectively
6 · The paper itself

Abstract

Three novel lipopeptides, PM130391 (1), PM130392 (2), and PM140293 (3) were obtained from cultures of

Indexed as

cytotoxic activitylipopeptidesnonribosomal peptides

Identifiers

PMID37887416
PMCPMC10609185
OpenAlexW4387737832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.