Evidence map›Paper›PMID 37887409›Full record

ArticleMetabolites2023

The Sterol Transporter Npc2c Controls Intestinal Stem Cell Mitosis and Host-Microbiome Interactions in

Constantina Neophytou, Euripides Soteriou, Chrysoula Pitsouli

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Fidelity in co-diversified symbiosis.Nature communications · 2026
    Article
  2. Starve-Feed Cycles Direct Quiescence to Proliferation Transitions inbioRxiv : the preprint server for biology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Constantina NeophytouDepartment of Biological Sciences, University of Cyprus, 1 University Avenue, 2109 Aglantzia, Cyprus.
Euripides SoteriouDepartment of Biological Sciences, University of Cyprus, 1 University Avenue, 2109 Aglantzia, Cyprus.
Chrysoula PitsouliDepartment of Biological Sciences, University of Cyprus, 1 University Avenue, 2109 Aglantzia, Cyprus.ORCID 0000-0003-4074-9684
University of Cyprus · CY

Funding

Cyprus Research and Innovation Foundation EXCELLENCE/0918/0082
6 · The paper itself

Abstract

Cholesterol is necessary for all cells to function. The intracellular cholesterol transporters Npc1 and Npc2 control sterol trafficking and their malfunction leads to Neimann-Pick Type C disease, a rare disorder affecting the nervous system and the intestine. Unlike humans that encode single Npc1 and Npc2 transporters, flies encompass two Npc1 (Npc1a-1b) and eight Npc2 (Npc2a-2h) members, and most of the

Indexed as

cholesteroldysbiosisecdysoneNpc2

Identifiers

PMID37887409
PMCPMC10609107
OpenAlexW4387672822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.