Evidence map›Paper›PMID 37887374›Full record

ArticleMetabolites2023

Exhaled Breath Analysis Using Selected Ion Flow Tube Mass Spectrometry and Disease Severity in Heart Failure.

Wai Hong Wilson Tang, Lily Tranchito, Chonyang Albert, Zeynep G Gul, Frank S Cikach, David Grove, Yuping Wu, Raed A Dweik

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wai Hong Wilson TangHeart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-8335-735X
Lily TranchitoEndocrinology & Metabolism Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Chonyang AlbertHeart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Zeynep G GulDepartment of Surgery, Washington University School of Medicine at St Louis, St Louis, MO 63110, USA.
Frank S CikachHeart Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
David GroveDepartment of Inflammation and Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Yuping WuDepartment of Mathematics, Cleveland State University, Cleveland, OH 44195, USA.
Raed A DweikDepartment of Inflammation and Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Cleveland Clinic · USCleveland State University · USWashington University in St. Louis · US

Funding

Nitrative stress in heart failureR01HL103931 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI TANG, WAI HONG WILSON · 2010 to 2014
$3.8M
NHLBI NIH HHS R01 HL103931
6 · The paper itself

Abstract

Exhaled breath volatile organic compounds (VOCs) are elevated in heart failure (HF). The ability of VOCs to predict long term cardiovascular mortality and morbidity has not been independently verified. In 55 patients admitted with acute decompensated heart failure (ADHF), we measured exhaled breath acetone and pentane levels upon admission and after 48 h of diuresis. In a separate cohort of 51 cardiac patients undergoing cardiopulmonary exercise testing (CPET), we measured exhaled breath acetone and pentane levels before and at peak exercise. In the ADHF cohort, admission acetone levels correlated with lower left ventricular ejection fraction (LVEF, r = -0.297,

Indexed as

acetoneexhaled breathheart failurepentaneselected ion flow tube mass spectrometry

Identifiers

PMID37887374
PMCPMC10608518
OpenAlexW4387307548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.