Evidence map›Paper›PMID 37887357›Full record

ArticleMetabolites2023

Hyperbaric Oxygen Therapy Counters Oxidative Stress/Inflammation-Driven Symptoms in Long COVID-19 Patients: Preliminary Outcomes.

Simona Mrakic-Sposta, Alessandra Vezzoli, Giacomo Garetto, Matteo Paganini, Enrico Camporesi, Tommaso Antonio Giacon, Cinzia Dellanoce, Jacopo Agrimi, Gerardo Bosco

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Oxy-inflammation in hyperbaric oxygen therapy applications.European journal of translational myology · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Simona Mrakic-SpostaInstitute of Clinical Physiology, National Research Council (IFC-CNR), 20162 Milan, Italy.ORCID 0000-0001-7359-2690
Alessandra VezzoliInstitute of Clinical Physiology, National Research Council (IFC-CNR), 20162 Milan, Italy.ORCID 0000-0002-0277-163X
Giacomo GarettoATIP Center for Hyperbaric Medicine, 35128 Padova, Italy.
Matteo PaganiniDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-7556-6928
Enrico CamporesiDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.ORCID 0000-0003-3548-1097
Tommaso Antonio GiaconDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-1155-0628
Cinzia DellanoceInstitute of Clinical Physiology, National Research Council (IFC-CNR), 20162 Milan, Italy.
Jacopo AgrimiDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.
Gerardo BoscoDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.ORCID 0000-0001-6595-7944
University of Padua · ITIstituto di Fisiologia Clinica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long COVID-19 patients show systemic inflammation and persistent symptoms such as fatigue and malaise, profoundly affecting their quality of life. Since improving oxygenation can oppose inflammation at multiple tissue levels, we hypothesized that hyperbaric oxygen therapy (HBOT) could arrest inflammation progression and thus relieve symptoms of COVID-19. We evaluated oxy-inflammation biomarkers in long COVID-19 subjects treated with HBOT and monitored with non-invasive methods. Five subjects (two athletes and three patients with other comorbidities) were assigned to receive HBOT: 100% inspired O

Indexed as

Electron Paramagnetic ResonanceHBOTinflammationlong COVID-19non-invasive methodsoxidative stressreactive oxygen speciessalivaurine

Identifiers

PMID37887357
PMCPMC10608857
OpenAlexW4387019769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.