Evidence map›Paper›PMID 37887323›Full record

ArticleCells2023

Effect of Hyperbaric Oxygen and Inflammation on Human Gingival Mesenchymal Stem/Progenitor Cells.

Johannes Tölle, Andreas Koch, Kristina Schlicht, Dirk Finger, Wataru Kaehler, Marc Höppner, Christian Graetz, Christof Dörfer, Dominik M Schulte, Karim Fawzy El-Sayed

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Johannes TölleClinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrechts-University, 24105 Kiel, Germany.ORCID 0000-0002-1755-2958
Andreas KochGerman Naval Medical Institute, 24119 Kiel, Germany.
Kristina SchlichtInstitute of Diabetes and Clinical Metabolic Research, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
Dirk FingerClinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrechts-University, 24105 Kiel, Germany.
Wataru KaehlerGerman Naval Medical Institute, 24119 Kiel, Germany.
Marc HöppnerInstitute of Clinical Molecular Biology, School of Medicine, Christian-Albrechts-University, 24105 Kiel, Germany.
Christian GraetzClinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrechts-University, 24105 Kiel, Germany.
Christof DörferClinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrechts-University, 24105 Kiel, Germany.ORCID 0000-0002-2508-8075
Dominik M SchulteInstitute of Diabetes and Clinical Metabolic Research, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
Karim Fawzy El-SayedClinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrechts-University, 24105 Kiel, Germany.ORCID 0000-0002-6261-3609
Christian-Albrechts-Universität zu Kiel · DESchifffahrtmedizinisches Institut der MarineUniversity Hospital Schleswig-Holstein · DECairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study explores for the first time the effect of hyperbaric oxygen (HBO) on gingival mesenchymal stem cells' (G-MSCs) gene expression profile, intracellular pathway activation, pluripotency, and differentiation potential under an experimental inflammatory setup. G-MSCs were isolated from five healthy individuals (

Indexed as

Hyperbaric OxygenationMesenchymal Stem CellsADP-Ribosylation FactorsAnti-Inflammatory AgentsHumansImmunologic FactorsInflammationOsteogenesisOxygenTolloid-Like MetalloproteinasesADP-Ribosylation FactorsAnti-Inflammatory AgentsARL4C protein, humanImmunologic FactorsOxygenTLL1 protein, humanTolloid-Like Metalloproteinaseshyperbaric oxygeninflammationnext-generation sequencingperiodontitisregenerationROSstem cells

Identifiers

PMID37887323
PMCPMC10605813
OpenAlexW4387738001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.