Evidence map›Paper›PMID 37887185›Full record

ArticleAntibiotics (Basel, Switzerland)2023

New Evidence for the Role of Pituitary Adenylate Cyclase-Activating Polypeptide as an Antimicrobial Peptide in Teleost Fish.

Janet Velázquez, Tania Rodríguez-Cornejo, Tania Rodríguez-Ramos, Geysi Pérez-Rodríguez, Laura Rivera, James Hugh Campbell, Lowia Al-Hussinee, Yamila Carpio, Mario Pablo Estrada, Brian Dixon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Unravelling turbot (Frontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Janet VelázquezAnimal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box 6162, Havana 10600, Cuba.ORCID 0000-0001-5445-6087
Tania Rodríguez-CornejoDepartment of Biology, University of Waterloo, 200 University Ave W., Waterloo, ON N2L 3G1, Canada.
Tania Rodríguez-RamosDepartment of Biology, University of Waterloo, 200 University Ave W., Waterloo, ON N2L 3G1, Canada.
Geysi Pérez-RodríguezAnimal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box 6162, Havana 10600, Cuba.
Laura RiveraDepartment of Biology, University of Waterloo, 200 University Ave W., Waterloo, ON N2L 3G1, Canada.
James Hugh CampbellDepartment of Biology, University of Waterloo, 200 University Ave W., Waterloo, ON N2L 3G1, Canada.
Lowia Al-HussineeDepartment of Biology, University of Waterloo, 200 University Ave W., Waterloo, ON N2L 3G1, Canada.
Yamila CarpioAnimal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box 6162, Havana 10600, Cuba.
Mario Pablo EstradaAnimal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), P.O. Box 6162, Havana 10600, Cuba.ORCID 0000-0002-9776-719X
Brian DixonDepartment of Biology, University of Waterloo, 200 University Ave W., Waterloo, ON N2L 3G1, Canada.ORCID 0000-0003-4213-5483
University of Waterloo · CACentro de Ingeniería Genética y Biotecnología · CU

Funding

Wellcome Trust 109054
6 · The paper itself

Abstract

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) is a multifunctional neuropeptide that is widely distributed and conserved across species. We have previously shown that in teleost fish, PACAP not only possesses direct antimicrobial properties but also immunomodulatory effects against the bacterial pathogens

Indexed as

antibacterial activityPACAPrainbow troutRTS11Yersinia ruckeri

Identifiers

PMID37887185
PMCPMC10604671
OpenAlexW4387121247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.